| pubmed-article:2651175 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2651175 | lifeskim:mentions | umls-concept:C0087111 | lld:lifeskim |
| pubmed-article:2651175 | lifeskim:mentions | umls-concept:C0038454 | lld:lifeskim |
| pubmed-article:2651175 | lifeskim:mentions | umls-concept:C0004153 | lld:lifeskim |
| pubmed-article:2651175 | lifeskim:mentions | umls-concept:C1708528 | lld:lifeskim |
| pubmed-article:2651175 | lifeskim:mentions | umls-concept:C0205195 | lld:lifeskim |
| pubmed-article:2651175 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:2651175 | pubmed:dateCreated | 1989-6-5 | lld:pubmed |
| pubmed-article:2651175 | pubmed:abstractText | This randomized, double-blind study on 79 patients reported the efficacy of ticlopidine-pentoxifylline combination in the treatment of atherosclerosis and the prevention of cerebrovascular accidents. Comparisons were made with aspirin-dipyridamole-buflomedil and buflomedil-placebo combinations as controls. Global symptoms, sensorimotor disorders and vertigo were improved in all treatment groups, although improvement tended to be more pronounced with ticlopidine-pentoxifylline. None of the groups showed any change in stenosis or vessel wall rigidity although ticlopidine-pentoxifylline reduced flow irregularity. This combination therapy also normalized the direction of flow in the ophthalmic artery in 46.2% of patients with retrograde flow prior to treatment, compared with 30.0% following aspirin-dipyridamole-buflomedil and 28.6% following buflomedil-placebo administration. Significantly fewer cerebrovascular accidents occurred after treatment with ticlopidine-pentoxifylline. In conclusion, ticlopidine-pentoxifylline showed good therapeutic efficacy against atherosclerosis and a preventative effect against new cerebrovascular accidents. This therapy was well tolerated. | lld:pubmed |
| pubmed-article:2651175 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2651175 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651175 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2651175 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:2651175 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651175 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:2651175 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2651175 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2651175 | pubmed:issn | 0300-0605 | lld:pubmed |
| pubmed-article:2651175 | pubmed:author | pubmed-author:MagriniLL | lld:pubmed |
| pubmed-article:2651175 | pubmed:author | pubmed-author:AngelettiRR | lld:pubmed |
| pubmed-article:2651175 | pubmed:author | pubmed-author:ApollonioAA | lld:pubmed |
| pubmed-article:2651175 | pubmed:author | pubmed-author:CastignaniPP | lld:pubmed |
| pubmed-article:2651175 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2651175 | pubmed:volume | 17 | lld:pubmed |
| pubmed-article:2651175 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2651175 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2651175 | pubmed:pagination | 28-35 | lld:pubmed |
| pubmed-article:2651175 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
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| pubmed-article:2651175 | pubmed:meshHeading | pubmed-meshheading:2651175-... | lld:pubmed |
| pubmed-article:2651175 | pubmed:articleTitle | Ticlopidine-pentoxifylline combination in the treatment of atherosclerosis and the prevention of cerebrovascular accidents. | lld:pubmed |
| pubmed-article:2651175 | pubmed:affiliation | Internal Medicine Department, Tarquinia Hospital, Italy. | lld:pubmed |
| pubmed-article:2651175 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2651175 | pubmed:publicationType | Clinical Trial | lld:pubmed |
| pubmed-article:2651175 | pubmed:publicationType | Randomized Controlled Trial | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2651175 | lld:pubmed |
