| pubmed-article:2642944 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2642944 | lifeskim:mentions | umls-concept:C0007806 | lld:lifeskim |
| pubmed-article:2642944 | lifeskim:mentions | umls-concept:C0085236 | lld:lifeskim |
| pubmed-article:2642944 | lifeskim:mentions | umls-concept:C0024432 | lld:lifeskim |
| pubmed-article:2642944 | lifeskim:mentions | umls-concept:C0038952 | lld:lifeskim |
| pubmed-article:2642944 | lifeskim:mentions | umls-concept:C2587213 | lld:lifeskim |
| pubmed-article:2642944 | lifeskim:mentions | umls-concept:C1515021 | lld:lifeskim |
| pubmed-article:2642944 | lifeskim:mentions | umls-concept:C1514485 | lld:lifeskim |
| pubmed-article:2642944 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:2642944 | pubmed:dateCreated | 1989-2-14 | lld:pubmed |
| pubmed-article:2642944 | pubmed:abstractText | The effect of granulocyte-macrophage (GM)-CSF on the proliferation of murine pulmonary alveolar macrophages in vitro was investigated. About 20% of freshly isolated alveolar macrophages formed colonies in both liquid and soft agar cultures in the presence of GM-CSF. GM-CSF was also found to be capable of maintaining the survival of these colony-forming cells in vitro. Moreover, GM-CSF could substitute for CSF-1 in maintaining the survival of CSF-1-responding pulmonary alveolar macrophage colony-forming cells in the absence of CSF-1. The concentration of GM-CSF required for maintaining the survival of colony-forming cells without proliferation was much lower than that required for the proliferation of these cells in vitro. It also enhanced the CSF-1-dependent clonal growth of alveolar macrophages. These data suggest that the colony-forming cells that respond to GM-CSF are the same subset of macrophages that form colonies in the presence of CSF-1. GM-CSF did not inhibit the binding of 125I-CSF-1 to alveolar macrophages at 0 degrees C. However, the preincubation of macrophages with GM-CSF at 37 degrees C resulted in a transient down-regulation of CSF-1 binding activity. | lld:pubmed |
| pubmed-article:2642944 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2642944 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2642944 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2642944 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2642944 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:2642944 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2642944 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2642944 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2642944 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2642944 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:2642944 | pubmed:issn | 0022-1767 | lld:pubmed |
| pubmed-article:2642944 | pubmed:author | pubmed-author:LinH SHS | lld:pubmed |
| pubmed-article:2642944 | pubmed:author | pubmed-author:HsuSS | lld:pubmed |
| pubmed-article:2642944 | pubmed:author | pubmed-author:LokeshwarB... | lld:pubmed |
| pubmed-article:2642944 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2642944 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:2642944 | pubmed:volume | 142 | lld:pubmed |
| pubmed-article:2642944 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2642944 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2642944 | pubmed:pagination | 515-9 | lld:pubmed |
| pubmed-article:2642944 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:2642944 | pubmed:meshHeading | pubmed-meshheading:2642944-... | lld:pubmed |
| pubmed-article:2642944 | pubmed:meshHeading | pubmed-meshheading:2642944-... | lld:pubmed |
| pubmed-article:2642944 | pubmed:meshHeading | pubmed-meshheading:2642944-... | lld:pubmed |
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| pubmed-article:2642944 | pubmed:meshHeading | pubmed-meshheading:2642944-... | lld:pubmed |
| pubmed-article:2642944 | pubmed:meshHeading | pubmed-meshheading:2642944-... | lld:pubmed |
| pubmed-article:2642944 | pubmed:meshHeading | pubmed-meshheading:2642944-... | lld:pubmed |
| pubmed-article:2642944 | pubmed:meshHeading | pubmed-meshheading:2642944-... | lld:pubmed |
| pubmed-article:2642944 | pubmed:meshHeading | pubmed-meshheading:2642944-... | lld:pubmed |
| pubmed-article:2642944 | pubmed:meshHeading | pubmed-meshheading:2642944-... | lld:pubmed |
| pubmed-article:2642944 | pubmed:meshHeading | pubmed-meshheading:2642944-... | lld:pubmed |
| pubmed-article:2642944 | pubmed:meshHeading | pubmed-meshheading:2642944-... | lld:pubmed |
| pubmed-article:2642944 | pubmed:meshHeading | pubmed-meshheading:2642944-... | lld:pubmed |
| pubmed-article:2642944 | pubmed:year | 1989 | lld:pubmed |
| pubmed-article:2642944 | pubmed:articleTitle | Both granulocyte-macrophage CSF and macrophage CSF control the proliferation and survival of the same subset of alveolar macrophages. | lld:pubmed |
| pubmed-article:2642944 | pubmed:affiliation | Division of Radiation Oncology, Mallinckrodt Institute of Radiology, St. Louis, MO 63110. | lld:pubmed |
| pubmed-article:2642944 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2642944 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2642944 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2642944 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2642944 | lld:pubmed |
