Linked Life Data

2580730

Source:http://linkedlifedata.com/resource/pubmed/id/2580730

Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:2580730rdf:typepubmed:Citationlld:pubmed
pubmed-article:2580730lifeskim:mentionsumls-concept:C0021757lld:lifeskim
pubmed-article:2580730lifeskim:mentionsumls-concept:C1522642lld:lifeskim
pubmed-article:2580730lifeskim:mentionsumls-concept:C0033684lld:lifeskim
pubmed-article:2580730lifeskim:mentionsumls-concept:C1171362lld:lifeskim
pubmed-article:2580730lifeskim:mentionsumls-concept:C0017262lld:lifeskim
pubmed-article:2580730lifeskim:mentionsumls-concept:C1515670lld:lifeskim
pubmed-article:2580730lifeskim:mentionsumls-concept:C1704222lld:lifeskim
pubmed-article:2580730lifeskim:mentionsumls-concept:C0205460lld:lifeskim
pubmed-article:2580730lifeskim:mentionsumls-concept:C2348205lld:lifeskim
pubmed-article:2580730lifeskim:mentionsumls-concept:C0591833lld:lifeskim
pubmed-article:2580730pubmed:issue4lld:pubmed
pubmed-article:2580730pubmed:dateCreated1985-5-30lld:pubmed
pubmed-article:2580730pubmed:abstractTextClonal lines of mouse inducer ly1+ly2- inducer T-lymphocytes that depend for growth upon interleukin-2 have been demonstrated to produce a factor that stimulates colony formation by bone marrow granulocyte-macrophage (GM-CFUc) progenitor cells and replication of factor-dependent mast cell/basophil and multipotential hematopoietic cell lines in vitro. The molecularly cloned and expressed gene product for this growth factor demonstrates the following activities in vitro: using fresh bone marrow or purified subpopulations of nonadherent cells from murine continuous bone marrow cultures as target cells: stimulation of colony formation by GM-CFUc, mast cell progenitor cells, multipotential granulocyte/erythroid/megakaryocyte/macrophage progenitor cells (CFU-GEMM) colonies, erythroid progenitor cells forming macroscopic bursts (BFUe), and megakaryocyte progenitor cells (CFU-mega). The gene product also supports growth of previously reported mast cell growth-factor-dependent cell lines and several classes of interleukin-3 (IL-3)-dependent hematopoietic progenitor cell lines that are multipotential (neutrophil/basophil/eosinophil or neutrophil/basophil/erythroid); or committed to granulocyte-macrophage, or mast cell/basophil differentiation. The gene product does not detectably support replication of IL-2-dependent murine T-cell lines. The biologic activity of the gene product was inhibited greater than or equal to 90% by rabbit antisera prepared against purified interleukin-3. The data indicate that this T-cell derived lymphokine gene product is biologically very similar to interleukin-3.lld:pubmed
pubmed-article:2580730pubmed:granthttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:2580730pubmed:granthttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:2580730pubmed:languageenglld:pubmed
pubmed-article:2580730pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:2580730pubmed:citationSubsetIMlld:pubmed
pubmed-article:2580730pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:2580730pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:2580730pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:2580730pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:2580730pubmed:statusMEDLINElld:pubmed
pubmed-article:2580730pubmed:monthMaylld:pubmed
pubmed-article:2580730pubmed:issn0301-472Xlld:pubmed
pubmed-article:2580730pubmed:authorpubmed-author:ReidD MDMlld:pubmed
pubmed-article:2580730pubmed:authorpubmed-author:GreenbergerJ...lld:pubmed
pubmed-article:2580730pubmed:authorpubmed-author:HumphriesR...lld:pubmed
pubmed-article:2580730pubmed:authorpubmed-author:MessnerHHlld:pubmed
pubmed-article:2580730pubmed:authorpubmed-author:SakakeenyM...lld:pubmed
pubmed-article:2580730pubmed:issnTypePrintlld:pubmed
pubmed-article:2580730pubmed:volume13lld:pubmed
pubmed-article:2580730pubmed:ownerNLMlld:pubmed
pubmed-article:2580730pubmed:authorsCompleteYlld:pubmed
pubmed-article:2580730pubmed:pagination249-60lld:pubmed
pubmed-article:2580730pubmed:dateRevised2007-11-14lld:pubmed
pubmed-article:2580730pubmed:meshHeadingpubmed-meshheading:2580730-...lld:pubmed
pubmed-article:2580730pubmed:meshHeadingpubmed-meshheading:2580730-...lld:pubmed
pubmed-article:2580730pubmed:meshHeadingpubmed-meshheading:2580730-...lld:pubmed
pubmed-article:2580730pubmed:meshHeadingpubmed-meshheading:2580730-...lld:pubmed
pubmed-article:2580730pubmed:meshHeadingpubmed-meshheading:2580730-...lld:pubmed
pubmed-article:2580730pubmed:meshHeadingpubmed-meshheading:2580730-...lld:pubmed
pubmed-article:2580730pubmed:meshHeadingpubmed-meshheading:2580730-...lld:pubmed
pubmed-article:2580730pubmed:meshHeadingpubmed-meshheading:2580730-...lld:pubmed
pubmed-article:2580730pubmed:meshHeadingpubmed-meshheading:2580730-...lld:pubmed
pubmed-article:2580730pubmed:meshHeadingpubmed-meshheading:2580730-...lld:pubmed
pubmed-article:2580730pubmed:meshHeadingpubmed-meshheading:2580730-...lld:pubmed
pubmed-article:2580730pubmed:meshHeadingpubmed-meshheading:2580730-...lld:pubmed
pubmed-article:2580730pubmed:meshHeadingpubmed-meshheading:2580730-...lld:pubmed
pubmed-article:2580730pubmed:meshHeadingpubmed-meshheading:2580730-...lld:pubmed
pubmed-article:2580730pubmed:year1985lld:pubmed
pubmed-article:2580730pubmed:articleTitleMolecularly cloned and expressed murine T-cell gene product is biologically similar to interleukin-3.lld:pubmed
pubmed-article:2580730pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:2580730pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
pubmed-article:2580730pubmed:publicationTypeResearch Support, U.S. Gov't, Non-P.H.S.lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:2580730lld:pubmed