| pubmed-article:2580040 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2580040 | lifeskim:mentions | umls-concept:C0004561 | lld:lifeskim |
| pubmed-article:2580040 | lifeskim:mentions | umls-concept:C0028778 | lld:lifeskim |
| pubmed-article:2580040 | lifeskim:mentions | umls-concept:C0178539 | lld:lifeskim |
| pubmed-article:2580040 | lifeskim:mentions | umls-concept:C1516349 | lld:lifeskim |
| pubmed-article:2580040 | lifeskim:mentions | umls-concept:C0008654 | lld:lifeskim |
| pubmed-article:2580040 | lifeskim:mentions | umls-concept:C1708726 | lld:lifeskim |
| pubmed-article:2580040 | lifeskim:mentions | umls-concept:C1704675 | lld:lifeskim |
| pubmed-article:2580040 | lifeskim:mentions | umls-concept:C0441655 | lld:lifeskim |
| pubmed-article:2580040 | lifeskim:mentions | umls-concept:C0443288 | lld:lifeskim |
| pubmed-article:2580040 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
| pubmed-article:2580040 | lifeskim:mentions | umls-concept:C0332206 | lld:lifeskim |
| pubmed-article:2580040 | lifeskim:mentions | umls-concept:C0205225 | lld:lifeskim |
| pubmed-article:2580040 | lifeskim:mentions | umls-concept:C1527178 | lld:lifeskim |
| pubmed-article:2580040 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:2580040 | pubmed:dateCreated | 1985-5-13 | lld:pubmed |
| pubmed-article:2580040 | pubmed:abstractText | The cellular mechanism and genetic restriction of neonatally induced HA-specific suppressor T (Ts) cells have been examined. The in vivo effect of these Ts cells on antibody production, primary B cell proliferation, B cell surface marker changes, and helper T (Th) cell priming during primary responses to HA have been determined. The results indicate that, although antigen-induced B cell proliferative responses and surface marker changes occur in the presence of Ts cells, differentiation to Ig secretion, and long-lived memory B cell production are prevented. Further, antigen-specific Th cell priming is completely ablated by Ts cells, suggesting that Ts act by preventing the delivery of Th signals required for both the later stages of primary B cell maturation, and the formation of memory B cell populations. Finally, in vivo cell mixing experiments using congenic mice indicate that this Ts-Th interaction is restricted by loci on mouse chromosome 12. | lld:pubmed |
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| pubmed-article:2580040 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2580040 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2580040 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:2580040 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2580040 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:2580040 | pubmed:issn | 0022-1007 | lld:pubmed |
| pubmed-article:2580040 | pubmed:author | pubmed-author:CancroM PMP | lld:pubmed |
| pubmed-article:2580040 | pubmed:author | pubmed-author:RaychaudhuriS... | lld:pubmed |
| pubmed-article:2580040 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2580040 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:2580040 | pubmed:volume | 161 | lld:pubmed |
| pubmed-article:2580040 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2580040 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2580040 | pubmed:pagination | 816-31 | lld:pubmed |
| pubmed-article:2580040 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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