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pubmed-article:2555149pubmed:abstractTextPsychological stress has been shown to affect immune system status and function, but most studies of this relationship have focused on acute stress and/or laboratory situations. The present study compared total numbers of leukocytes and lymphocyte subpopulations (determined by flow cytometry) and antibody titers to latent and nonlatent viruses among a group of chronically stressed individuals living near the damaged Three Mile Island (TMI) nuclear power plant with those of a demographically comparable control group. Urinary catecholamine and cortisol levels were also examined. Residents of the TMI area exhibited greater numbers of neutrophils, which were positively correlated with epinephrine levels. The TMI group also exhibited fewer B lymphocytes, T-suppressor/cytotoxic lymphocytes, and natural killer cells. Antibody titers to herpes simplex were significantly different across groups as well, whereas titers to nonlatent rubella virus as well as IgG and IgM levels were comparable.lld:pubmed
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pubmed-article:2555149pubmed:articleTitleChronic stress, leukocyte subpopulations, and humoral response to latent viruses.lld:pubmed
pubmed-article:2555149pubmed:affiliationUniformed Services University of the Health Sciences, Bethesda, MD 20814-4799.lld:pubmed
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pubmed-article:2555149pubmed:publicationTypeResearch Support, U.S. Gov't, Non-P.H.S.lld:pubmed
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