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pubmed-article:2553496pubmed:abstractTextSpatial and temporal expression pattern of retinoic acid receptor (RAR) genes was investigated in mouse finger bones during development by an in situ hybridization method with riboprobes synthesized from a human cDNA of the RAR-alpha. We found that the RAR genes are expressed intensively and specifically in calcifying fronts of the mouse finger bones, whereas the expression pattern is rather uniform in the limb buds and cartilage matrices of the embryonic fingers. Our findings are consistent with the fact that vitamin A is essential for normal mammalian bone development.lld:pubmed
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pubmed-article:2553496pubmed:articleTitleSpatial and temporal expression pattern of retinoic acid receptor genes during mouse bone development.lld:pubmed
pubmed-article:2553496pubmed:affiliationOkayama University Dental School, Okayama City, Japan.lld:pubmed
pubmed-article:2553496pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:2553496pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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