| pubmed-article:2547585 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2547585 | lifeskim:mentions | umls-concept:C0034721 | lld:lifeskim |
| pubmed-article:2547585 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:2547585 | lifeskim:mentions | umls-concept:C0042518 | lld:lifeskim |
| pubmed-article:2547585 | lifeskim:mentions | umls-concept:C0040223 | lld:lifeskim |
| pubmed-article:2547585 | lifeskim:mentions | umls-concept:C1751535 | lld:lifeskim |
| pubmed-article:2547585 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
| pubmed-article:2547585 | lifeskim:mentions | umls-concept:C0750729 | lld:lifeskim |
| pubmed-article:2547585 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:2547585 | pubmed:dateCreated | 1989-9-20 | lld:pubmed |
| pubmed-article:2547585 | pubmed:abstractText | Oxytocin (OT) transmission is involved in the steroid-dependent display of sexual receptivity in rats. One of the biochemical processes stimulated by the ovarian steroid 17 beta-estradiol (E2) that is relevant to reproduction is the induction of OT receptor binding in the ventromedial hypothalamic nucleus (VMN). The purpose of these experiments was to determine if E2-induced changes in OT receptor binding in the VMN occur within a time frame relevant to cyclic changes in ovarian steroid secretion. OT receptor binding was measured in the VMN of ovariectomized rats implanted for 0-96 h with E2-containing Silastic capsules. The rate of decay of OT receptor binding was measured in another group of animals 6-48 h after capsule removal. Receptors were labeled with the specific OT receptor antagonist [125I]d(CH2)5[Tyr(Me)2,Thr4,Tyr-NH2(9)]OVT, and binding was measured with quantitative autoradiographic methods. In addition, plasma E2 levels and uterine weights were assessed in animals from each treatment condition. Significant increases in E2-dependent OT receptor binding and uterine weight occurred within 24 h of steroid treatment. After E2 withdrawal, OT receptor binding and uterine weight decreased significantly within 24 h. These results are consistent with the hypothesis that steroid modulation of OT receptor binding is necessary for the induction of sexual receptivity. | lld:pubmed |
| pubmed-article:2547585 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2547585 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2547585 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2547585 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2547585 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:2547585 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2547585 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2547585 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2547585 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2547585 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2547585 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2547585 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2547585 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:2547585 | pubmed:issn | 0013-7227 | lld:pubmed |
| pubmed-article:2547585 | pubmed:author | pubmed-author:McEwenB SBS | lld:pubmed |
| pubmed-article:2547585 | pubmed:author | pubmed-author:JohnsonA EAE | lld:pubmed |
| pubmed-article:2547585 | pubmed:author | pubmed-author:InselT RTR | lld:pubmed |
| pubmed-article:2547585 | pubmed:author | pubmed-author:CoiriniHH | lld:pubmed |
| pubmed-article:2547585 | pubmed:author | pubmed-author:BallG FGF | lld:pubmed |
| pubmed-article:2547585 | pubmed:author | pubmed-author:HarbaughC RCR | lld:pubmed |
| pubmed-article:2547585 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2547585 | pubmed:volume | 125 | lld:pubmed |
| pubmed-article:2547585 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2547585 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2547585 | pubmed:pagination | 1414-9 | lld:pubmed |
| pubmed-article:2547585 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
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| pubmed-article:2547585 | pubmed:meshHeading | pubmed-meshheading:2547585-... | lld:pubmed |
| pubmed-article:2547585 | pubmed:year | 1989 | lld:pubmed |
| pubmed-article:2547585 | pubmed:articleTitle | Time course of the estradiol-dependent induction of oxytocin receptor binding in the ventromedial hypothalamic nucleus of the rat. | lld:pubmed |
| pubmed-article:2547585 | pubmed:affiliation | Section on Comparative Studies of Brain and Behavior, National Institute of Mental Health, Poolesville, Maryland 20837. | lld:pubmed |
| pubmed-article:2547585 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2547585 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:2547585 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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