pubmed-article:2537735 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:2537735 | lifeskim:mentions | umls-concept:C0039194 | lld:lifeskim |
pubmed-article:2537735 | lifeskim:mentions | umls-concept:C0034790 | lld:lifeskim |
pubmed-article:2537735 | lifeskim:mentions | umls-concept:C0205245 | lld:lifeskim |
pubmed-article:2537735 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
pubmed-article:2537735 | lifeskim:mentions | umls-concept:C1332709 | lld:lifeskim |
pubmed-article:2537735 | lifeskim:mentions | umls-concept:C1823153 | lld:lifeskim |
pubmed-article:2537735 | lifeskim:mentions | umls-concept:C2349976 | lld:lifeskim |
pubmed-article:2537735 | lifeskim:mentions | umls-concept:C1552644 | lld:lifeskim |
pubmed-article:2537735 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
pubmed-article:2537735 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
pubmed-article:2537735 | pubmed:issue | 1 | lld:pubmed |
pubmed-article:2537735 | pubmed:dateCreated | 1989-4-17 | lld:pubmed |
pubmed-article:2537735 | pubmed:abstractText | T lymphocytes express a T cell antigen receptor (TcR) complex composed of either an TcR alpha/beta or TcR gamma/delta heterodimer in noncovalent association with the CD3 glycoproteins. CD28, a 44-kDa disulfide-linked homodimer, is present on the surface of the majority of TcR alpha/beta-bearing T lymphocytes. Monoclonal antibodies (mAb) directed against CD28 potentiate activation signals delivered through the CD3/TcR alpha/beta complex. Herein, we demonstrate that CD28 is expressed on approximately 40%-60% of TcR gamma/delta-bearing T lymphocytes in most donors. Anti-CD28 mAb substantially augmented proliferative signals delivered through the TcR gamma/delta, demonstrating the presence of functional CD28 molecules on TcR gamma/delta-bearing T lymphocytes. The majority of TcR gamma/delta+ thymocytes also expressed CD28. | lld:pubmed |
pubmed-article:2537735 | pubmed:language | eng | lld:pubmed |
pubmed-article:2537735 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2537735 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:2537735 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2537735 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2537735 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2537735 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2537735 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:2537735 | pubmed:month | Jan | lld:pubmed |
pubmed-article:2537735 | pubmed:issn | 0014-2980 | lld:pubmed |
pubmed-article:2537735 | pubmed:author | pubmed-author:LanierL LLL | lld:pubmed |
pubmed-article:2537735 | pubmed:author | pubmed-author:TestaJJ | lld:pubmed |
pubmed-article:2537735 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:2537735 | pubmed:volume | 19 | lld:pubmed |
pubmed-article:2537735 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:2537735 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:2537735 | pubmed:pagination | 185-8 | lld:pubmed |
pubmed-article:2537735 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
pubmed-article:2537735 | pubmed:meshHeading | pubmed-meshheading:2537735-... | lld:pubmed |
pubmed-article:2537735 | pubmed:meshHeading | pubmed-meshheading:2537735-... | lld:pubmed |
pubmed-article:2537735 | pubmed:meshHeading | pubmed-meshheading:2537735-... | lld:pubmed |
pubmed-article:2537735 | pubmed:meshHeading | pubmed-meshheading:2537735-... | lld:pubmed |
pubmed-article:2537735 | pubmed:meshHeading | pubmed-meshheading:2537735-... | lld:pubmed |
pubmed-article:2537735 | pubmed:meshHeading | pubmed-meshheading:2537735-... | lld:pubmed |
pubmed-article:2537735 | pubmed:meshHeading | pubmed-meshheading:2537735-... | lld:pubmed |
pubmed-article:2537735 | pubmed:meshHeading | pubmed-meshheading:2537735-... | lld:pubmed |
pubmed-article:2537735 | pubmed:meshHeading | pubmed-meshheading:2537735-... | lld:pubmed |
pubmed-article:2537735 | pubmed:meshHeading | pubmed-meshheading:2537735-... | lld:pubmed |
pubmed-article:2537735 | pubmed:year | 1989 | lld:pubmed |
pubmed-article:2537735 | pubmed:articleTitle | Functional expression of CD28 on T cell antigen receptor gamma/delta-bearing T lymphocytes. | lld:pubmed |
pubmed-article:2537735 | pubmed:affiliation | Becton Dickinson Monoclonal Center Inc., Mountain View, CA 94043. | lld:pubmed |
pubmed-article:2537735 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:2537735 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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