| pubmed-article:2532990 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2532990 | lifeskim:mentions | umls-concept:C0003873 | lld:lifeskim |
| pubmed-article:2532990 | lifeskim:mentions | umls-concept:C0024141 | lld:lifeskim |
| pubmed-article:2532990 | lifeskim:mentions | umls-concept:C0004561 | lld:lifeskim |
| pubmed-article:2532990 | lifeskim:mentions | umls-concept:C1155003 | lld:lifeskim |
| pubmed-article:2532990 | lifeskim:mentions | umls-concept:C0020846 | lld:lifeskim |
| pubmed-article:2532990 | lifeskim:mentions | umls-concept:C0597357 | lld:lifeskim |
| pubmed-article:2532990 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:2532990 | lifeskim:mentions | umls-concept:C1414549 | lld:lifeskim |
| pubmed-article:2532990 | lifeskim:mentions | umls-concept:C0205100 | lld:lifeskim |
| pubmed-article:2532990 | lifeskim:mentions | umls-concept:C1521805 | lld:lifeskim |
| pubmed-article:2532990 | lifeskim:mentions | umls-concept:C0441712 | lld:lifeskim |
| pubmed-article:2532990 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:2532990 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:2532990 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:2532990 | pubmed:dateCreated | 1990-2-27 | lld:pubmed |
| pubmed-article:2532990 | pubmed:abstractText | To clarify the differential state of B cell activation in patients with systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA), we investigated the expression of low-affinity receptor for IgE (Fc epsilon RII; CD23) on their peripheral B cells by a cytofluorometry using H107 (CD23) and Leu-16 (CD20) monoclonal antibodies. The percentage of CD23-negative B cells in total lymphocytes was significantly greater in both groups of patients than in normal subjects, suggesting the hyperactivity of late-phase B cells in both diseases. However, the increase of CD23-negative B cells in RA was brought about by the increased number of total B cells, although that in SLE was mainly based on the relative decrease of CD23-positive B cells. The number of IgD-positive B cells was decreased, and the number of colony-forming B cells was markedly increased in SLE patients. These observations indicate that a B cell abnormality is mainly qualitative in SLE but quantitative in RA. | lld:pubmed |
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| pubmed-article:2532990 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2532990 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2532990 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:2532990 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2532990 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:2532990 | pubmed:issn | 0009-9104 | lld:pubmed |
| pubmed-article:2532990 | pubmed:author | pubmed-author:IshidaHH | lld:pubmed |
| pubmed-article:2532990 | pubmed:author | pubmed-author:ArayaSS | lld:pubmed |
| pubmed-article:2532990 | pubmed:author | pubmed-author:IwaiKK | lld:pubmed |
| pubmed-article:2532990 | pubmed:author | pubmed-author:ImuraHH | lld:pubmed |
| pubmed-article:2532990 | pubmed:author | pubmed-author:OzakiSS | lld:pubmed |
| pubmed-article:2532990 | pubmed:author | pubmed-author:KumagaiSS | lld:pubmed |
| pubmed-article:2532990 | pubmed:author | pubmed-author:TsubataTT | lld:pubmed |
| pubmed-article:2532990 | pubmed:author | pubmed-author:UmeharaHH | lld:pubmed |
| pubmed-article:2532990 | pubmed:author | pubmed-author:SuginoshitaTT | lld:pubmed |
| pubmed-article:2532990 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2532990 | pubmed:volume | 78 | lld:pubmed |
| pubmed-article:2532990 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2532990 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2532990 | pubmed:pagination | 348-53 | lld:pubmed |
| pubmed-article:2532990 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:2532990 | pubmed:meshHeading | pubmed-meshheading:2532990-... | lld:pubmed |
| pubmed-article:2532990 | pubmed:year | 1989 | lld:pubmed |
| pubmed-article:2532990 | pubmed:articleTitle | Possible different mechanisms of B cell activation in systemic lupus erythematosus and rheumatoid arthritis: opposite expression of low-affinity receptors for IgE (CD23) on their peripheral B cells. | lld:pubmed |
| pubmed-article:2532990 | pubmed:affiliation | Second Division of Internal Medicine, Kyoto University Medical School, Japan. | lld:pubmed |
| pubmed-article:2532990 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2532990 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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