| pubmed-article:2523389 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2523389 | lifeskim:mentions | umls-concept:C0024660 | lld:lifeskim |
| pubmed-article:2523389 | lifeskim:mentions | umls-concept:C1267092 | lld:lifeskim |
| pubmed-article:2523389 | lifeskim:mentions | umls-concept:C0009017 | lld:lifeskim |
| pubmed-article:2523389 | lifeskim:mentions | umls-concept:C2262324 | lld:lifeskim |
| pubmed-article:2523389 | pubmed:issue | 12 | lld:pubmed |
| pubmed-article:2523389 | pubmed:dateCreated | 1989-6-2 | lld:pubmed |
| pubmed-article:2523389 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2523389 | pubmed:abstractText | We have isolated and sequenced full-length cDNA clones from a rabbit uterine library which encode the smooth muscle sarco(endo)plasmic reticulum Ca2+-ATPase. These cDNAs resulted from an alternative splice of the cardiac/slow-twitch Ca2+-ATPase gene transcript, and encoded a protein identical to rabbit cardiac/slow-twitch Ca2+-ATPase except for the replacement of the carboxyl-terminal four amino acids with an extended and relatively hydrophobic sequence of 49 amino acids. This cDNA was virtually identical to the alternatively spliced product of the cardiac/slow-twitch Ca2+-ATPase gene recently identified in human kidney (Lytton, J., and MacLennan, D. H. (1988) J. Biol. Chem. 263, 15024-15031) and rat non-muscle tissues (Gunteski-Hamblin, A.-M., Greeb, J., and Shull, G. (1988) J. Biol. Chem. 263, 15032-15040). S1 nuclease mapping of total cellular RNA from a variety of tissues demonstrated that cardiac muscle expressed the cardiac/slow-twitch isoform almost exclusively, most smooth muscle and non-muscle tissues expressed the alternatively spliced smooth/non-muscle isoform almost exclusively, and a few tissues expressed both isoforms in varying amounts. Thus, regulation of alternative splicing of the cardiac/slow-twitch Ca2+-ATPase gene transcript is tissue-specific. The expression of the smooth/non-muscle isoform in every tissue tested supports the hypothesis that this molecule represents the "housekeeping" endoplasmic reticulum Ca2+-ATPase. | lld:pubmed |
| pubmed-article:2523389 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2523389 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2523389 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2523389 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2523389 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2523389 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2523389 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2523389 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2523389 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:2523389 | pubmed:issn | 0021-9258 | lld:pubmed |
| pubmed-article:2523389 | pubmed:author | pubmed-author:PeriasamyMM | lld:pubmed |
| pubmed-article:2523389 | pubmed:author | pubmed-author:MacLennanD... | lld:pubmed |
| pubmed-article:2523389 | pubmed:author | pubmed-author:LyttonJJ | lld:pubmed |
| pubmed-article:2523389 | pubmed:author | pubmed-author:Zarain-Herzbe... | lld:pubmed |
| pubmed-article:2523389 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2523389 | pubmed:day | 25 | lld:pubmed |
| pubmed-article:2523389 | pubmed:volume | 264 | lld:pubmed |
| pubmed-article:2523389 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2523389 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2523389 | pubmed:pagination | 7059-65 | lld:pubmed |
| pubmed-article:2523389 | pubmed:dateRevised | 2010-11-18 | lld:pubmed |
| pubmed-article:2523389 | pubmed:meshHeading | pubmed-meshheading:2523389-... | lld:pubmed |
| pubmed-article:2523389 | pubmed:meshHeading | pubmed-meshheading:2523389-... | lld:pubmed |
| pubmed-article:2523389 | pubmed:meshHeading | pubmed-meshheading:2523389-... | lld:pubmed |
| pubmed-article:2523389 | pubmed:meshHeading | pubmed-meshheading:2523389-... | lld:pubmed |
| pubmed-article:2523389 | pubmed:meshHeading | pubmed-meshheading:2523389-... | lld:pubmed |
| pubmed-article:2523389 | pubmed:meshHeading | pubmed-meshheading:2523389-... | lld:pubmed |
| pubmed-article:2523389 | pubmed:meshHeading | pubmed-meshheading:2523389-... | lld:pubmed |
| pubmed-article:2523389 | pubmed:meshHeading | pubmed-meshheading:2523389-... | lld:pubmed |
| pubmed-article:2523389 | pubmed:meshHeading | pubmed-meshheading:2523389-... | lld:pubmed |
| pubmed-article:2523389 | pubmed:meshHeading | pubmed-meshheading:2523389-... | lld:pubmed |
| pubmed-article:2523389 | pubmed:meshHeading | pubmed-meshheading:2523389-... | lld:pubmed |
| pubmed-article:2523389 | pubmed:meshHeading | pubmed-meshheading:2523389-... | lld:pubmed |
| pubmed-article:2523389 | pubmed:meshHeading | pubmed-meshheading:2523389-... | lld:pubmed |
| pubmed-article:2523389 | pubmed:meshHeading | pubmed-meshheading:2523389-... | lld:pubmed |
| pubmed-article:2523389 | pubmed:year | 1989 | lld:pubmed |
| pubmed-article:2523389 | pubmed:articleTitle | Molecular cloning of the mammalian smooth muscle sarco(endo)plasmic reticulum Ca2+-ATPase. | lld:pubmed |
| pubmed-article:2523389 | pubmed:affiliation | Banting and Best Department of Medical Research, University of Toronto, Ontario, Canada. | lld:pubmed |
| pubmed-article:2523389 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2523389 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:2523389 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:2523389 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:100038308 | entrezgene:pubmed | pubmed-article:2523389 | lld:entrezgene |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2523389 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2523389 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2523389 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2523389 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2523389 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2523389 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2523389 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2523389 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2523389 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2523389 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2523389 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2523389 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2523389 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2523389 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2523389 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2523389 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2523389 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2523389 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2523389 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2523389 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2523389 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2523389 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2523389 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2523389 | lld:pubmed |
