pubmed-article:2523358 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:2523358 | lifeskim:mentions | umls-concept:C0020846 | lld:lifeskim |
pubmed-article:2523358 | lifeskim:mentions | umls-concept:C0597357 | lld:lifeskim |
pubmed-article:2523358 | lifeskim:mentions | umls-concept:C1704675 | lld:lifeskim |
pubmed-article:2523358 | lifeskim:mentions | umls-concept:C0678594 | lld:lifeskim |
pubmed-article:2523358 | lifeskim:mentions | umls-concept:C1704419 | lld:lifeskim |
pubmed-article:2523358 | lifeskim:mentions | umls-concept:C1514873 | lld:lifeskim |
pubmed-article:2523358 | lifeskim:mentions | umls-concept:C1527178 | lld:lifeskim |
pubmed-article:2523358 | pubmed:issue | 1-2 | lld:pubmed |
pubmed-article:2523358 | pubmed:dateCreated | 1989-6-2 | lld:pubmed |
pubmed-article:2523358 | pubmed:abstractText | Structural interactions between IgE and its high-affinity receptor have been investigated with the methods of fluorescence resonance energy transfer and genetic engineering. The results indicate that IgE has a bent conformation when bound to receptor on the cell surface and that the site of interaction is contained in the C epsilon 2 and C epsilon 3 domains; the C-terminal domain, C epsilon 4, is not required for binding. Cross-linking of IgE-receptor complexes is required for signal transduction across the plasma membrane. Binding studies with defined bivalent ligands indicate that structural and/or kinetic features determine the functional effectiveness of the cross-linked states. | lld:pubmed |
pubmed-article:2523358 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2523358 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2523358 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2523358 | pubmed:language | eng | lld:pubmed |
pubmed-article:2523358 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2523358 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:2523358 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2523358 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2523358 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2523358 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2523358 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2523358 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2523358 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:2523358 | pubmed:issn | 0020-5915 | lld:pubmed |
pubmed-article:2523358 | pubmed:author | pubmed-author:EricksonJJ | lld:pubmed |
pubmed-article:2523358 | pubmed:author | pubmed-author:OiV TVT | lld:pubmed |
pubmed-article:2523358 | pubmed:author | pubmed-author:KanePP | lld:pubmed |
pubmed-article:2523358 | pubmed:author | pubmed-author:HolowkaDD | lld:pubmed |
pubmed-article:2523358 | pubmed:author | pubmed-author:BairdBB | lld:pubmed |
pubmed-article:2523358 | pubmed:author | pubmed-author:ShopesR JRJ | lld:pubmed |
pubmed-article:2523358 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:2523358 | pubmed:volume | 88 | lld:pubmed |
pubmed-article:2523358 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:2523358 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:2523358 | pubmed:pagination | 23-8 | lld:pubmed |
pubmed-article:2523358 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
pubmed-article:2523358 | pubmed:meshHeading | pubmed-meshheading:2523358-... | lld:pubmed |
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pubmed-article:2523358 | pubmed:meshHeading | pubmed-meshheading:2523358-... | lld:pubmed |
pubmed-article:2523358 | pubmed:year | 1989 | lld:pubmed |
pubmed-article:2523358 | pubmed:articleTitle | Interaction of IgE with its high-affinity receptor. Structural basis and requirements for effective cross-linking. | lld:pubmed |
pubmed-article:2523358 | pubmed:affiliation | Department of Chemistry, Baker Laboratory, Cornell University, Ithaca, N.Y. | lld:pubmed |
pubmed-article:2523358 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:2523358 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
pubmed-article:2523358 | pubmed:publicationType | Review | lld:pubmed |
pubmed-article:2523358 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2523358 | lld:pubmed |