pubmed-article:2508273 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:2508273 | lifeskim:mentions | umls-concept:C0087111 | lld:lifeskim |
pubmed-article:2508273 | lifeskim:mentions | umls-concept:C0026336 | lld:lifeskim |
pubmed-article:2508273 | lifeskim:mentions | umls-concept:C0016890 | lld:lifeskim |
pubmed-article:2508273 | lifeskim:mentions | umls-concept:C0040549 | lld:lifeskim |
pubmed-article:2508273 | lifeskim:mentions | umls-concept:C0441472 | lld:lifeskim |
pubmed-article:2508273 | lifeskim:mentions | umls-concept:C0442805 | lld:lifeskim |
pubmed-article:2508273 | lifeskim:mentions | umls-concept:C1509144 | lld:lifeskim |
pubmed-article:2508273 | lifeskim:mentions | umls-concept:C1516469 | lld:lifeskim |
pubmed-article:2508273 | lifeskim:mentions | umls-concept:C0205266 | lld:lifeskim |
pubmed-article:2508273 | lifeskim:mentions | umls-concept:C0337051 | lld:lifeskim |
pubmed-article:2508273 | pubmed:issue | 9 | lld:pubmed |
pubmed-article:2508273 | pubmed:dateCreated | 1989-11-20 | lld:pubmed |
pubmed-article:2508273 | pubmed:abstractText | Botulinum C2 toxin ADP-ribosylates actin in intact chicken embryo cells in a concentration-dependent manner. This effect correlates with an enhancement in the inhibitory potency of the respective cell lysates on DNAse I activity, indicating an increase in the cellular G-actin content of toxin-treated cells. The data support our view, that ADP-ribosylation of cellular actin with subsequent depolymerization of cytoskeleton-associated F-actin to monomeric G-actin is involved in the cytotoxic effects of botulinum C2 toxin. A model of the cytopathic action of actin-ADP-ribosylating toxins is presented. | lld:pubmed |
pubmed-article:2508273 | pubmed:language | eng | lld:pubmed |
pubmed-article:2508273 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2508273 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:2508273 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2508273 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2508273 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2508273 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2508273 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2508273 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:2508273 | pubmed:issn | 0041-0101 | lld:pubmed |
pubmed-article:2508273 | pubmed:author | pubmed-author:PresekPP | lld:pubmed |
pubmed-article:2508273 | pubmed:author | pubmed-author:AktoriesKK | lld:pubmed |
pubmed-article:2508273 | pubmed:author | pubmed-author:ReunerK HKH | lld:pubmed |
pubmed-article:2508273 | pubmed:author | pubmed-author:BärmannMM | lld:pubmed |
pubmed-article:2508273 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:2508273 | pubmed:volume | 27 | lld:pubmed |
pubmed-article:2508273 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:2508273 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:2508273 | pubmed:pagination | 989-93 | lld:pubmed |
pubmed-article:2508273 | pubmed:dateRevised | 2010-11-18 | lld:pubmed |
pubmed-article:2508273 | pubmed:meshHeading | pubmed-meshheading:2508273-... | lld:pubmed |
pubmed-article:2508273 | pubmed:meshHeading | pubmed-meshheading:2508273-... | lld:pubmed |
pubmed-article:2508273 | pubmed:meshHeading | pubmed-meshheading:2508273-... | lld:pubmed |
pubmed-article:2508273 | pubmed:meshHeading | pubmed-meshheading:2508273-... | lld:pubmed |
pubmed-article:2508273 | pubmed:meshHeading | pubmed-meshheading:2508273-... | lld:pubmed |
pubmed-article:2508273 | pubmed:meshHeading | pubmed-meshheading:2508273-... | lld:pubmed |
pubmed-article:2508273 | pubmed:meshHeading | pubmed-meshheading:2508273-... | lld:pubmed |
pubmed-article:2508273 | pubmed:meshHeading | pubmed-meshheading:2508273-... | lld:pubmed |
pubmed-article:2508273 | pubmed:meshHeading | pubmed-meshheading:2508273-... | lld:pubmed |
pubmed-article:2508273 | pubmed:year | 1989 | lld:pubmed |
pubmed-article:2508273 | pubmed:articleTitle | Botulinum C2 toxin treatment increases the G-actin pool in intact chicken cells: a model for the cytopathic action of actin-ADP-ribosylating toxins. | lld:pubmed |
pubmed-article:2508273 | pubmed:affiliation | Rudolf-Buchheim-Institut für Pharmakologie, Universität Giessen, F.R.G. | lld:pubmed |
pubmed-article:2508273 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:2508273 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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