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pubmed-article:2506702pubmed:abstractTextIn a clinical study efficacy and tolerance of Neogluconin (2.5 mg) a new galenical form of glibenclamide were compared with a conventional preparation (Euglucon 5). Neogluconin showed an improved absorption and comparable blood sugar levels at a dosage reduced by 25%. 25 outpatients suffering from Type II diabetes in a well balanced metabolic state and previously under Euglucon therapy for at least one year were changed to the new product. After 2 months of Neogluconin therapy blood sugar profiles, HbA1, C-peptide and cholesterin levels were unchanged in comparison to values determined during the previous Euglucon treatment. This confirms that Neogluconin produces a comparable favorable blood glucose lowering effect despite a 25% reduction in dosage.lld:pubmed
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pubmed-article:2506702pubmed:articleTitle[Clinical study comparing the effectiveness and tolerance of 2 current and one new glibenclamide formulation].lld:pubmed
pubmed-article:2506702pubmed:affiliationInterne Abteilung, a. ö. Krankenhaus, Dornbirn.lld:pubmed
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