pubmed-article:2506372 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:2506372 | lifeskim:mentions | umls-concept:C0030883 | lld:lifeskim |
pubmed-article:2506372 | lifeskim:mentions | umls-concept:C0243026 | lld:lifeskim |
pubmed-article:2506372 | lifeskim:mentions | umls-concept:C0332161 | lld:lifeskim |
pubmed-article:2506372 | lifeskim:mentions | umls-concept:C0235432 | lld:lifeskim |
pubmed-article:2506372 | pubmed:issue | 4 | lld:pubmed |
pubmed-article:2506372 | pubmed:dateCreated | 1989-10-25 | lld:pubmed |
pubmed-article:2506372 | pubmed:abstractText | Pentobarbital therapy has been associated with decreased urinary nitrogen excretion and resting energy expenditure in stressed patients. The metabolic effects of pentobarbital in sepsis were investigated in 29 well-nourished rats who underwent superior vena caval cannulation, cecal ligation, and puncture. Animals were randomly assigned to receive either a continuous infusion of 20 mg/kg/day of pentobarbital combined with parenteral nutrition (n = 13) or parenteral nutrition alone (n = 16). Both groups received isocaloric, isonitrogenous parenteral nutrition postoperatively for 24 hr. Mean nitrogen balance (+/- SEM) was better in the pentobarbital group (+169 +/- 76 mg/kg/day vs -190 +/- 66 mg/kg/day, p less than 0.01). No significant differences between the pentobarbital and control groups were noted for urinary 3-methylhistidine excretion (9 +/- 0.7 micrograms/kg/day vs 11 +/- 0.6 micrograms/kg/day, respectively) or 24 hr survival (77% vs 69%, respectively). Pentobarbital improves nitrogen retention without decreasing urinary 3-methylhistidine excretion in septic rats. | lld:pubmed |
pubmed-article:2506372 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2506372 | pubmed:language | eng | lld:pubmed |
pubmed-article:2506372 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2506372 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:2506372 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2506372 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2506372 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:2506372 | pubmed:issn | 0148-6071 | lld:pubmed |
pubmed-article:2506372 | pubmed:author | pubmed-author:MullerJ HJH | lld:pubmed |
pubmed-article:2506372 | pubmed:author | pubmed-author:BuzbyG PGP | lld:pubmed |
pubmed-article:2506372 | pubmed:author | pubmed-author:SteinT PTP | lld:pubmed |
pubmed-article:2506372 | pubmed:author | pubmed-author:FriedR CRC | lld:pubmed |
pubmed-article:2506372 | pubmed:author | pubmed-author:DickersonR... | lld:pubmed |
pubmed-article:2506372 | pubmed:author | pubmed-author:DanielM GMG | lld:pubmed |
pubmed-article:2506372 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:2506372 | pubmed:volume | 13 | lld:pubmed |
pubmed-article:2506372 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:2506372 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:2506372 | pubmed:pagination | 359-61 | lld:pubmed |
pubmed-article:2506372 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
pubmed-article:2506372 | pubmed:meshHeading | pubmed-meshheading:2506372-... | lld:pubmed |
pubmed-article:2506372 | pubmed:meshHeading | pubmed-meshheading:2506372-... | lld:pubmed |
pubmed-article:2506372 | pubmed:meshHeading | pubmed-meshheading:2506372-... | lld:pubmed |
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pubmed-article:2506372 | pubmed:meshHeading | pubmed-meshheading:2506372-... | lld:pubmed |
pubmed-article:2506372 | pubmed:meshHeading | pubmed-meshheading:2506372-... | lld:pubmed |
pubmed-article:2506372 | pubmed:meshHeading | pubmed-meshheading:2506372-... | lld:pubmed |
pubmed-article:2506372 | pubmed:meshHeading | pubmed-meshheading:2506372-... | lld:pubmed |
pubmed-article:2506372 | pubmed:meshHeading | pubmed-meshheading:2506372-... | lld:pubmed |
pubmed-article:2506372 | pubmed:articleTitle | Pentobarbital improves nitrogen retention in sepsis. | lld:pubmed |
pubmed-article:2506372 | pubmed:affiliation | Department of Surgery, University of Pennsylvania School of Medicine, Philadelphia. | lld:pubmed |
pubmed-article:2506372 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:2506372 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
pubmed-article:2506372 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
pubmed-article:2506372 | pubmed:publicationType | Review | lld:pubmed |
pubmed-article:2506372 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |