| pubmed-article:2500363 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2500363 | lifeskim:mentions | umls-concept:C0597357 | lld:lifeskim |
| pubmed-article:2500363 | lifeskim:mentions | umls-concept:C0003241 | lld:lifeskim |
| pubmed-article:2500363 | lifeskim:mentions | umls-concept:C0205245 | lld:lifeskim |
| pubmed-article:2500363 | lifeskim:mentions | umls-concept:C1704675 | lld:lifeskim |
| pubmed-article:2500363 | lifeskim:mentions | umls-concept:C2003941 | lld:lifeskim |
| pubmed-article:2500363 | lifeskim:mentions | umls-concept:C2603343 | lld:lifeskim |
| pubmed-article:2500363 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:2500363 | pubmed:dateCreated | 1989-7-28 | lld:pubmed |
| pubmed-article:2500363 | pubmed:abstractText | Antibodies generated to a synthetic decapeptide, RMHLRQYELL, representing the carboxyl-terminus of Gs-alpha have been characterized in immunoblots and functional studies. This antibody, designated RM, reacts exclusively with a doublet of proteins of 52 and 45 kDa in immunoblots of bovine brain and wild-type S49 murine lymphoma cell membranes. No such reactivity is seen in membranes from cyc- S49 cells, which lack Gs. RM blocks receptor-mediated activation of Gs and adenylyl cyclase in membranes from wild-type S49 cells. RM could also immunoprecipitate adenylyl cyclase activity in detergent extracts from GTP[gamma]S- or fluoride-preactivated bovine brain membranes; thus binding of alpha s to effector and carboxyl-terminal antibody was mutually compatible. Such experiments provide an approach for the elucidation of functionally relevant interactions of G-proteins with receptors and effectors in the membrane. | lld:pubmed |
| pubmed-article:2500363 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2500363 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2500363 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2500363 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2500363 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2500363 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2500363 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2500363 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2500363 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:2500363 | pubmed:issn | 0014-5793 | lld:pubmed |
| pubmed-article:2500363 | pubmed:author | pubmed-author:WoodardC JCJ | lld:pubmed |
| pubmed-article:2500363 | pubmed:author | pubmed-author:SpiegelA MAM | lld:pubmed |
| pubmed-article:2500363 | pubmed:author | pubmed-author:GoldsmithP... | lld:pubmed |
| pubmed-article:2500363 | pubmed:author | pubmed-author:SimondsW FWF | lld:pubmed |
| pubmed-article:2500363 | pubmed:author | pubmed-author:UnsonC GCG | lld:pubmed |
| pubmed-article:2500363 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2500363 | pubmed:day | 5 | lld:pubmed |
| pubmed-article:2500363 | pubmed:volume | 249 | lld:pubmed |
| pubmed-article:2500363 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2500363 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2500363 | pubmed:pagination | 189-94 | lld:pubmed |
| pubmed-article:2500363 | pubmed:dateRevised | 2003-11-14 | lld:pubmed |
| pubmed-article:2500363 | pubmed:meshHeading | pubmed-meshheading:2500363-... | lld:pubmed |
| pubmed-article:2500363 | pubmed:meshHeading | pubmed-meshheading:2500363-... | lld:pubmed |
| pubmed-article:2500363 | pubmed:meshHeading | pubmed-meshheading:2500363-... | lld:pubmed |
| pubmed-article:2500363 | pubmed:meshHeading | pubmed-meshheading:2500363-... | lld:pubmed |
| pubmed-article:2500363 | pubmed:meshHeading | pubmed-meshheading:2500363-... | lld:pubmed |
| pubmed-article:2500363 | pubmed:meshHeading | pubmed-meshheading:2500363-... | lld:pubmed |
| pubmed-article:2500363 | pubmed:meshHeading | pubmed-meshheading:2500363-... | lld:pubmed |
| pubmed-article:2500363 | pubmed:meshHeading | pubmed-meshheading:2500363-... | lld:pubmed |
| pubmed-article:2500363 | pubmed:meshHeading | pubmed-meshheading:2500363-... | lld:pubmed |
| pubmed-article:2500363 | pubmed:meshHeading | pubmed-meshheading:2500363-... | lld:pubmed |
| pubmed-article:2500363 | pubmed:meshHeading | pubmed-meshheading:2500363-... | lld:pubmed |
| pubmed-article:2500363 | pubmed:meshHeading | pubmed-meshheading:2500363-... | lld:pubmed |
| pubmed-article:2500363 | pubmed:year | 1989 | lld:pubmed |
| pubmed-article:2500363 | pubmed:articleTitle | Receptor and effector interactions of Gs. Functional studies with antibodies to the alpha s carboxyl-terminal decapeptide. | lld:pubmed |
| pubmed-article:2500363 | pubmed:affiliation | Molecular Pathophysiology Branch, National Institute of Diabetes, Digestive and Kidney Diseases, Bethesda, MD 20892. | lld:pubmed |
| pubmed-article:2500363 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2500363 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2500363 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2500363 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2500363 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2500363 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2500363 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2500363 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2500363 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2500363 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2500363 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2500363 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2500363 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2500363 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2500363 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2500363 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2500363 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2500363 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2500363 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2500363 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2500363 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2500363 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2500363 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2500363 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2500363 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2500363 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2500363 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2500363 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2500363 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2500363 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2500363 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2500363 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2500363 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2500363 | lld:pubmed |
