| pubmed-article:2497618 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2497618 | lifeskim:mentions | umls-concept:C0521346 | lld:lifeskim |
| pubmed-article:2497618 | lifeskim:mentions | umls-concept:C0278134 | lld:lifeskim |
| pubmed-article:2497618 | lifeskim:mentions | umls-concept:C0022180 | lld:lifeskim |
| pubmed-article:2497618 | lifeskim:mentions | umls-concept:C0028215 | lld:lifeskim |
| pubmed-article:2497618 | lifeskim:mentions | umls-concept:C1521970 | lld:lifeskim |
| pubmed-article:2497618 | lifeskim:mentions | umls-concept:C0806140 | lld:lifeskim |
| pubmed-article:2497618 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:2497618 | pubmed:dateCreated | 1989-6-22 | lld:pubmed |
| pubmed-article:2497618 | pubmed:abstractText | Ventilatory characteristics during isoflurane anaesthesia and spontaneous breathing were studied in ten adults during surgery. After premedication with diazepam and induction with thiopental sodium and suxamethonium, 1.2% isoflurane in a 50% mixture of nitrous oxide in oxygen was introduced via a non-rebreathing circuit. Respiratory flow was measured by means of a pneumotachograph, arterial gases were sampled and carbon dioxide elimination and dead-space to tidal volume ratios (VD/VT) calculated. The time axis of one respiratory cycle was divided into 20 equidistant sections and the flow at the end of each section was expressed as a percentage of the maximum flow rate during inspiration and expiration, respectively. In this manner, a relative respiratory flow pattern was constructed. The total ventilation was 5.8 +/- 0.5 1.min-1 (mean +/- s.d.) with a tidal volume of 191 +/- 45 ml and a respiratory rate of 31 +/- 6.min-1. The PaCO2 was 7.2 +/- 0.6 kPa, the carbon dioxide elimination 151 +/- 38 ml (STPD) and VD/VT 0.53 +/- 0.12. The respiratory flow pattern showed early peak flows during both inspiration and expiration. The expiratory flow rate after 90% of the total respiratory cycle time was on average 43% of the maximum expiratory flow rate. The conclusion was that isoflurane seems to have a similar respiratory flow pattern to halothane. The significant hypercarbia that resulted is still acceptable but a lighter anaesthetic level is recommended for routine surgery. | lld:pubmed |
| pubmed-article:2497618 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2497618 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2497618 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2497618 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2497618 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2497618 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2497618 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2497618 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2497618 | pubmed:month | May | lld:pubmed |
| pubmed-article:2497618 | pubmed:issn | 0001-5172 | lld:pubmed |
| pubmed-article:2497618 | pubmed:author | pubmed-author:JonssonL OLO | lld:pubmed |
| pubmed-article:2497618 | pubmed:author | pubmed-author:WahlgreenCC | lld:pubmed |
| pubmed-article:2497618 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2497618 | pubmed:volume | 33 | lld:pubmed |
| pubmed-article:2497618 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2497618 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2497618 | pubmed:pagination | 331-5 | lld:pubmed |
| pubmed-article:2497618 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:2497618 | pubmed:meshHeading | pubmed-meshheading:2497618-... | lld:pubmed |
| pubmed-article:2497618 | pubmed:meshHeading | pubmed-meshheading:2497618-... | lld:pubmed |
| pubmed-article:2497618 | pubmed:meshHeading | pubmed-meshheading:2497618-... | lld:pubmed |
| pubmed-article:2497618 | pubmed:meshHeading | pubmed-meshheading:2497618-... | lld:pubmed |
| pubmed-article:2497618 | pubmed:meshHeading | pubmed-meshheading:2497618-... | lld:pubmed |
| pubmed-article:2497618 | pubmed:meshHeading | pubmed-meshheading:2497618-... | lld:pubmed |
| pubmed-article:2497618 | pubmed:meshHeading | pubmed-meshheading:2497618-... | lld:pubmed |
| pubmed-article:2497618 | pubmed:meshHeading | pubmed-meshheading:2497618-... | lld:pubmed |
| pubmed-article:2497618 | pubmed:meshHeading | pubmed-meshheading:2497618-... | lld:pubmed |
| pubmed-article:2497618 | pubmed:meshHeading | pubmed-meshheading:2497618-... | lld:pubmed |
| pubmed-article:2497618 | pubmed:meshHeading | pubmed-meshheading:2497618-... | lld:pubmed |
| pubmed-article:2497618 | pubmed:meshHeading | pubmed-meshheading:2497618-... | lld:pubmed |
| pubmed-article:2497618 | pubmed:meshHeading | pubmed-meshheading:2497618-... | lld:pubmed |
| pubmed-article:2497618 | pubmed:year | 1989 | lld:pubmed |
| pubmed-article:2497618 | pubmed:articleTitle | Respiratory flow characteristics during isoflurane/nitrous oxide anaesthesia. | lld:pubmed |
| pubmed-article:2497618 | pubmed:affiliation | Department of Anaesthesiology and Intensive Care, Ostersund Hospital, Sweden. | lld:pubmed |
| pubmed-article:2497618 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2497618 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
