| pubmed-article:2495226 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2495226 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:2495226 | lifeskim:mentions | umls-concept:C0010674 | lld:lifeskim |
| pubmed-article:2495226 | lifeskim:mentions | umls-concept:C0033809 | lld:lifeskim |
| pubmed-article:2495226 | lifeskim:mentions | umls-concept:C0012893 | lld:lifeskim |
| pubmed-article:2495226 | lifeskim:mentions | umls-concept:C0546816 | lld:lifeskim |
| pubmed-article:2495226 | lifeskim:mentions | umls-concept:C1524063 | lld:lifeskim |
| pubmed-article:2495226 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:2495226 | pubmed:dateCreated | 1989-5-19 | lld:pubmed |
| pubmed-article:2495226 | pubmed:abstractText | To investigate cross-colonization with and persistence of Pseudomonas aeruginosa in cystic fibrosis (CF), 181 isolates from 76 CF patients were typed using a P. aeruginosa-specific DNA probe. Whereas sibling pairs predominantly harboured genotypically identical P. aeruginosa strains, all of the other patients harboured different strains. Seventy-nine per cent (22/31) of the infected CF patients harboured the same strains at the beginning and the end of a summer camp. A change of strains was seen in 10% (3/31) of the patients at the end of the camp. Forty-six per cent (6/13) of the patients who were apparently initially uninfected, acquired P. aeruginosa by the end of the period. Genotyping proved that strain change or acquisition was due to cross-colonization in four of nine cases. Very little P. aeruginosa was isolated from the inanimate environment. Persistence of P. aeruginosa after a temporary loss due to antibiotic therapy was seen in 12/16 paired patient strains before and after antibiotic therapy. Thus, suppression followed a flare-up seemed to occur in these patients rather than eradication and a new infection. When 35 patients were followed over a period of 6 months, 7 (20%) changed the strain in their sputum. Only one of 43 patients harboured two different P. aeruginosa strains simultaneously over a long period. | lld:pubmed |
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| pubmed-article:2495226 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2495226 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2495226 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:2495226 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2495226 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:2495226 | pubmed:issn | 0950-2688 | lld:pubmed |
| pubmed-article:2495226 | pubmed:author | pubmed-author:SchaafWW | lld:pubmed |
| pubmed-article:2495226 | pubmed:author | pubmed-author:VasilM LML | lld:pubmed |
| pubmed-article:2495226 | pubmed:author | pubmed-author:OgleJ WJW | lld:pubmed |
| pubmed-article:2495226 | pubmed:author | pubmed-author:BotzenhartKK | lld:pubmed |
| pubmed-article:2495226 | pubmed:author | pubmed-author:DöringGG | lld:pubmed |
| pubmed-article:2495226 | pubmed:author | pubmed-author:WolzCC | lld:pubmed |
| pubmed-article:2495226 | pubmed:author | pubmed-author:KioszGG | lld:pubmed |
| pubmed-article:2495226 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2495226 | pubmed:volume | 102 | lld:pubmed |
| pubmed-article:2495226 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2495226 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2495226 | pubmed:pagination | 205-14 | lld:pubmed |
| pubmed-article:2495226 | pubmed:dateRevised | 2010-9-7 | lld:pubmed |
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| pubmed-article:2495226 | pubmed:year | 1989 | lld:pubmed |
| pubmed-article:2495226 | pubmed:articleTitle | Pseudomonas aeruginosa cross-colonization and persistence in patients with cystic fibrosis. Use of a DNA probe. | lld:pubmed |
| pubmed-article:2495226 | pubmed:affiliation | Hygiene Institute, University of Tübingen, Federal Republic of Germany. | lld:pubmed |
| pubmed-article:2495226 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2495226 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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