A single base mutation that substitutes serine for glycine 790 of the alpha 1 (III) chain of type III procollagen exposes an arginine and causes Ehlers-Danlos syndrome IV.

Source:http://linkedlifedata.com/resource/pubmed/id/2492273

J. Biol. Chem. 1989 Jan 25 264 3 1349-52

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2492273