| pubmed-article:2481937 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2481937 | lifeskim:mentions | umls-concept:C0238462 | lld:lifeskim |
| pubmed-article:2481937 | lifeskim:mentions | umls-concept:C0549473 | lld:lifeskim |
| pubmed-article:2481937 | lifeskim:mentions | umls-concept:C0439682 | lld:lifeskim |
| pubmed-article:2481937 | lifeskim:mentions | umls-concept:C0205419 | lld:lifeskim |
| pubmed-article:2481937 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:2481937 | pubmed:dateCreated | 1990-2-22 | lld:pubmed |
| pubmed-article:2481937 | pubmed:abstractText | A case of C cell carcinoma of the thyroid with an unusual follicular growth pattern of the cancerous C cells is described. The primary tumor consisted of a mixture of medullary and follicular features while the metastatic foci in the lymph nodes and liver displayed only a medullary arrangement. Histochemical study disclosed numerous argyrophilic cells in both the follicular and medullary parts. These cells were immunohistochemically positive for calcitonin, calcitonin gene-related peptide (CGRP) and other peptides as well as carcinoembryonic antigen (CEA), but negative for thyroglobulin. Radioimmunoassay done on the tissue extract revealed a high content of calcitonin. Electron microscopy showed small intracytoplasmic secretory granules and, in the follicular lining cells, formation of microvilli. A minor component consisting of glandular structures has been reported in medullary carcinoma of the thyroid, suggesting a potentiality for glandular differentiation of the C cells. In equivocal cases, immunohistochemical examination for calcitonin and thyroglobulin is essential for accurate diagnosis of thyroid carcinoma. | lld:pubmed |
| pubmed-article:2481937 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2481937 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2481937 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2481937 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2481937 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2481937 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2481937 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2481937 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2481937 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2481937 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2481937 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2481937 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2481937 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:2481937 | pubmed:issn | 0001-6632 | lld:pubmed |
| pubmed-article:2481937 | pubmed:author | pubmed-author:WatanabeKK | lld:pubmed |
| pubmed-article:2481937 | pubmed:author | pubmed-author:KubotaMM | lld:pubmed |
| pubmed-article:2481937 | pubmed:author | pubmed-author:TadaNN | lld:pubmed |
| pubmed-article:2481937 | pubmed:author | pubmed-author:OsamuraYY | lld:pubmed |
| pubmed-article:2481937 | pubmed:author | pubmed-author:NakamuraAA | lld:pubmed |
| pubmed-article:2481937 | pubmed:author | pubmed-author:KakudoKK | lld:pubmed |
| pubmed-article:2481937 | pubmed:author | pubmed-author:Lertprasertsu... | lld:pubmed |
| pubmed-article:2481937 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2481937 | pubmed:volume | 39 | lld:pubmed |
| pubmed-article:2481937 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2481937 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2481937 | pubmed:pagination | 393-9 | lld:pubmed |
| pubmed-article:2481937 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:2481937 | pubmed:meshHeading | pubmed-meshheading:2481937-... | lld:pubmed |
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| pubmed-article:2481937 | pubmed:meshHeading | pubmed-meshheading:2481937-... | lld:pubmed |
| pubmed-article:2481937 | pubmed:year | 1989 | lld:pubmed |
| pubmed-article:2481937 | pubmed:articleTitle | C cell carcinoma of the thyroid. Follicular variant. | lld:pubmed |
| pubmed-article:2481937 | pubmed:affiliation | Department of Pathology, Tokai University, School of Medicine, Isehara, Japan. | lld:pubmed |
| pubmed-article:2481937 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2481937 | pubmed:publicationType | Case Reports | lld:pubmed |
