| pubmed-article:2479543 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2479543 | lifeskim:mentions | umls-concept:C0003284 | lld:lifeskim |
| pubmed-article:2479543 | lifeskim:mentions | umls-concept:C0035711 | lld:lifeskim |
| pubmed-article:2479543 | lifeskim:mentions | umls-concept:C1537998 | lld:lifeskim |
| pubmed-article:2479543 | lifeskim:mentions | umls-concept:C1514562 | lld:lifeskim |
| pubmed-article:2479543 | lifeskim:mentions | umls-concept:C1883221 | lld:lifeskim |
| pubmed-article:2479543 | lifeskim:mentions | umls-concept:C1883204 | lld:lifeskim |
| pubmed-article:2479543 | lifeskim:mentions | umls-concept:C1880389 | lld:lifeskim |
| pubmed-article:2479543 | lifeskim:mentions | umls-concept:C0121925 | lld:lifeskim |
| pubmed-article:2479543 | lifeskim:mentions | umls-concept:C0206415 | lld:lifeskim |
| pubmed-article:2479543 | pubmed:issue | 11 | lld:pubmed |
| pubmed-article:2479543 | pubmed:dateCreated | 1989-12-29 | lld:pubmed |
| pubmed-article:2479543 | pubmed:abstractText | The virion cores of the replication competent type 1 human immunodeficiency virus (HIV-1), a retrovirus, contain and RNA genome associated with nucleocapsid (NC) and reverse transcriptase (RT p66/p51) molecules. In vitro reconstructions of these complexes with purified components show that NC is required for efficient annealing of the primer tRNALys,3. In the absence of NC, HIV-1 RT is unable to retrotranscribe the viral RNA template from the tRNA primer. We demonstrate that the HIV-1 RT p66/p51 specifically binds to its cognate primer tRNALys,3 even in the presence of a 100-fold molar excess of other tRNAs. Cross-linking analysis of this interaction locates the contact site to a region within the heavily modified anti-codon domain of tRNALys,3. | lld:pubmed |
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| pubmed-article:2479543 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2479543 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2479543 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:2479543 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2479543 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:2479543 | pubmed:issn | 0261-4189 | lld:pubmed |
| pubmed-article:2479543 | pubmed:author | pubmed-author:KeithGG | lld:pubmed |
| pubmed-article:2479543 | pubmed:author | pubmed-author:DarlixJ LJL | lld:pubmed |
| pubmed-article:2479543 | pubmed:author | pubmed-author:Barré-Sinouss... | lld:pubmed |
| pubmed-article:2479543 | pubmed:author | pubmed-author:BaranEE | lld:pubmed |
| pubmed-article:2479543 | pubmed:author | pubmed-author:SchatzOO | lld:pubmed |
| pubmed-article:2479543 | pubmed:author | pubmed-author:LullienVV | lld:pubmed |
| pubmed-article:2479543 | pubmed:author | pubmed-author:Grüninger-Lei... | lld:pubmed |
| pubmed-article:2479543 | pubmed:author | pubmed-author:NugeyreM TMT | lld:pubmed |
| pubmed-article:2479543 | pubmed:author | pubmed-author:LeGriceS FSF | lld:pubmed |
| pubmed-article:2479543 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2479543 | pubmed:volume | 8 | lld:pubmed |
| pubmed-article:2479543 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2479543 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2479543 | pubmed:pagination | 3279-85 | lld:pubmed |
| pubmed-article:2479543 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:2479543 | pubmed:meshHeading | pubmed-meshheading:2479543-... | lld:pubmed |
| pubmed-article:2479543 | pubmed:year | 1989 | lld:pubmed |
