| pubmed-article:2473321 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2473321 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:2473321 | lifeskim:mentions | umls-concept:C0079281 | lld:lifeskim |
| pubmed-article:2473321 | lifeskim:mentions | umls-concept:C1801960 | lld:lifeskim |
| pubmed-article:2473321 | lifeskim:mentions | umls-concept:C0302523 | lld:lifeskim |
| pubmed-article:2473321 | lifeskim:mentions | umls-concept:C0700325 | lld:lifeskim |
| pubmed-article:2473321 | lifeskim:mentions | umls-concept:C1704632 | lld:lifeskim |
| pubmed-article:2473321 | lifeskim:mentions | umls-concept:C0871261 | lld:lifeskim |
| pubmed-article:2473321 | lifeskim:mentions | umls-concept:C2911692 | lld:lifeskim |
| pubmed-article:2473321 | lifeskim:mentions | umls-concept:C1706817 | lld:lifeskim |
| pubmed-article:2473321 | lifeskim:mentions | umls-concept:C1533691 | lld:lifeskim |
| pubmed-article:2473321 | lifeskim:mentions | umls-concept:C1515655 | lld:lifeskim |
| pubmed-article:2473321 | pubmed:dateCreated | 1989-8-21 | lld:pubmed |
| pubmed-article:2473321 | pubmed:abstractText | These studies have investigated the effect of endothelin-1 (ET-1) on human resistance vasculature in vivo and in vitro. ET-1 was infused via the brachial artery and forearm blood flow (FBF) measured by venous occlusion plethysmography. Isolated resistance vessels were studied in a myograph. ET-1 (10 pmol-10 nmol/min, i.a.) reduced forearm blood flow. Endothelin-1-induced forearm vasoconstriction was slow to recover following washout. ET-1 (10 pM-10 nM) contracted isolated human subcutaneous and omental resistance vessels. Contractile responses to ET-1 were sustained and washout recovery was slow. Responses to ET-1 displayed marked tachyphylaxis. Calcium channel blockers and removal of extracellular calcium failed to completely abolish responses to ET-1 in vitro. | lld:pubmed |
| pubmed-article:2473321 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2473321 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2473321 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2473321 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2473321 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2473321 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2473321 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2473321 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2473321 | pubmed:issn | 0160-2446 | lld:pubmed |
| pubmed-article:2473321 | pubmed:author | pubmed-author:SeverP SPS | lld:pubmed |
| pubmed-article:2473321 | pubmed:author | pubmed-author:SchachterMM | lld:pubmed |
| pubmed-article:2473321 | pubmed:author | pubmed-author:HughesA DAD | lld:pubmed |
| pubmed-article:2473321 | pubmed:author | pubmed-author:MartinG NGN | lld:pubmed |
| pubmed-article:2473321 | pubmed:author | pubmed-author:HolmI EIE | lld:pubmed |
| pubmed-article:2473321 | pubmed:author | pubmed-author:ThomS ASA | lld:pubmed |
| pubmed-article:2473321 | pubmed:author | pubmed-author:WoodallNN | lld:pubmed |
| pubmed-article:2473321 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2473321 | pubmed:volume | 13 Suppl 5 | lld:pubmed |
| pubmed-article:2473321 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2473321 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2473321 | pubmed:pagination | S225-8 | lld:pubmed |
| pubmed-article:2473321 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:2473321 | pubmed:meshHeading | pubmed-meshheading:2473321-... | lld:pubmed |
| pubmed-article:2473321 | pubmed:meshHeading | pubmed-meshheading:2473321-... | lld:pubmed |
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| pubmed-article:2473321 | pubmed:meshHeading | pubmed-meshheading:2473321-... | lld:pubmed |
| pubmed-article:2473321 | pubmed:meshHeading | pubmed-meshheading:2473321-... | lld:pubmed |
| pubmed-article:2473321 | pubmed:meshHeading | pubmed-meshheading:2473321-... | lld:pubmed |
| pubmed-article:2473321 | pubmed:meshHeading | pubmed-meshheading:2473321-... | lld:pubmed |
| pubmed-article:2473321 | pubmed:meshHeading | pubmed-meshheading:2473321-... | lld:pubmed |
| pubmed-article:2473321 | pubmed:meshHeading | pubmed-meshheading:2473321-... | lld:pubmed |
| pubmed-article:2473321 | pubmed:meshHeading | pubmed-meshheading:2473321-... | lld:pubmed |
| pubmed-article:2473321 | pubmed:meshHeading | pubmed-meshheading:2473321-... | lld:pubmed |
| pubmed-article:2473321 | pubmed:year | 1989 | lld:pubmed |
| pubmed-article:2473321 | pubmed:articleTitle | Human vascular responses to endothelin-1: observations in vivo and in vitro. | lld:pubmed |
| pubmed-article:2473321 | pubmed:affiliation | Department of Clinical Pharmacology, St. Mary's Hospital Medical School, London, England. | lld:pubmed |
| pubmed-article:2473321 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2473321 | pubmed:publicationType | In Vitro | lld:pubmed |
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