| pubmed-article:2463464 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2463464 | lifeskim:mentions | umls-concept:C0007634 | lld:lifeskim |
| pubmed-article:2463464 | lifeskim:mentions | umls-concept:C1522449 | lld:lifeskim |
| pubmed-article:2463464 | lifeskim:mentions | umls-concept:C0035804 | lld:lifeskim |
| pubmed-article:2463464 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
| pubmed-article:2463464 | lifeskim:mentions | umls-concept:C1707511 | lld:lifeskim |
| pubmed-article:2463464 | lifeskim:mentions | umls-concept:C0025548 | lld:lifeskim |
| pubmed-article:2463464 | pubmed:issue | 11 | lld:pubmed |
| pubmed-article:2463464 | pubmed:dateCreated | 1989-2-23 | lld:pubmed |
| pubmed-article:2463464 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2463464 | pubmed:abstractText | Sequence analysis of Chinese hamster V79 lung fibroblast cDNA clones, which code for UV radiation-inducible transcripts, revealed that many of the clones corresponded to metallothioneins (MTs) I and II. A third cDNA clone, DDIU4, was found also to code for a similar-size UV-inducible transcript which was unrelated to MT by both sequence analysis and kinetics of induction. MTI and MTII RNAs rapidly increased in V79 cells within 1 h after UV irradiation, and maximum induction was seen by 4 h. This rapid induction of MT RNA by UV irradiation was not observed in human fibroblasts. MTI and MTII were coordinately induced in both time course and dose-response experiments, although the induction of MTII, up to 30-fold, was three to four times greater than that of MTI. The induction of MT did not appear to be a general stress response, since no increase occurred after exposure to X rays or H2O2. | lld:pubmed |
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| pubmed-article:2463464 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2463464 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2463464 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:2463464 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2463464 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:2463464 | pubmed:issn | 0270-7306 | lld:pubmed |
| pubmed-article:2463464 | pubmed:author | pubmed-author:FornaceA... | lld:pubmed |
| pubmed-article:2463464 | pubmed:author | pubmed-author:AlamoIIJr | lld:pubmed |
| pubmed-article:2463464 | pubmed:author | pubmed-author:SchalchHH | lld:pubmed |
| pubmed-article:2463464 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2463464 | pubmed:volume | 8 | lld:pubmed |
| pubmed-article:2463464 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2463464 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2463464 | pubmed:pagination | 4716-20 | lld:pubmed |
| pubmed-article:2463464 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:2463464 | pubmed:year | 1988 | lld:pubmed |
| pubmed-article:2463464 | pubmed:articleTitle | Coordinate induction of metallothioneins I and II in rodent cells by UV irradiation. | lld:pubmed |
| pubmed-article:2463464 | pubmed:affiliation | Radiation Oncology Branch, National Cancer Institute, Bethesda, Maryland 20892. | lld:pubmed |
| pubmed-article:2463464 | pubmed:publicationType | Journal Article | lld:pubmed |
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