| pubmed-article:2456125 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2456125 | lifeskim:mentions | umls-concept:C0034721 | lld:lifeskim |
| pubmed-article:2456125 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:2456125 | lifeskim:mentions | umls-concept:C0027882 | lld:lifeskim |
| pubmed-article:2456125 | lifeskim:mentions | umls-concept:C0004461 | lld:lifeskim |
| pubmed-article:2456125 | lifeskim:mentions | umls-concept:C0033063 | lld:lifeskim |
| pubmed-article:2456125 | lifeskim:mentions | umls-concept:C0023610 | lld:lifeskim |
| pubmed-article:2456125 | lifeskim:mentions | umls-concept:C1441616 | lld:lifeskim |
| pubmed-article:2456125 | lifeskim:mentions | umls-concept:C0332120 | lld:lifeskim |
| pubmed-article:2456125 | lifeskim:mentions | umls-concept:C0449379 | lld:lifeskim |
| pubmed-article:2456125 | pubmed:issue | 1-2 | lld:pubmed |
| pubmed-article:2456125 | pubmed:dateCreated | 1988-8-31 | lld:pubmed |
| pubmed-article:2456125 | pubmed:abstractText | Connections between adrenocorticotropic hormone (ACTH)-immunoreactive neurons in the arcuate nucleus and the preoptic area were studied in the female rat. ACTH-immunopositive terminals were observed in the medial preoptic area in contact with dendritic shafts, while in the ventrolateral preoptic area the majority of ACTH-immunoreactive synapses were found on dendritic spines. Double-label electron microscopic immunocytochemistry using peroxidase and avidin-ferritin as contrasting electron-dense markers revealed numerous synaptic contacts between ACTH-immunopositive boutons and luteinizing hormone-releasing hormone (LH-RH)-immunoreactive dendritic shafts in the medial preoptic area. Following injection of horseradish peroxidase (HRP) into the medial preoptic area, retrogradely HRP-labeled perikarya were observed throughout the arcuate nucleus. Double-staining experiments revealed that a proportion of these retrogradely labeled cells, in the ventromedial arcuate nucleus, are also immunoreactive for ACTH. These results suggest that pro-opiomelanocortin peptide-producing neurons in the ventromedial arcuate nucleus project to the medial preoptic area. Some of these neurons establish direct synaptic contacts with LH-RH-immunoreactive cells. | lld:pubmed |
| pubmed-article:2456125 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2456125 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2456125 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2456125 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2456125 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2456125 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2456125 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2456125 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2456125 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2456125 | pubmed:month | May | lld:pubmed |
| pubmed-article:2456125 | pubmed:issn | 0006-8993 | lld:pubmed |
| pubmed-article:2456125 | pubmed:author | pubmed-author:NaftolinFF | lld:pubmed |
| pubmed-article:2456125 | pubmed:author | pubmed-author:MacLuskyN JNJ | lld:pubmed |
| pubmed-article:2456125 | pubmed:author | pubmed-author:LeranthCC | lld:pubmed |
| pubmed-article:2456125 | pubmed:author | pubmed-author:ShanabroughMM | lld:pubmed |
| pubmed-article:2456125 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2456125 | pubmed:day | 24 | lld:pubmed |
| pubmed-article:2456125 | pubmed:volume | 449 | lld:pubmed |
| pubmed-article:2456125 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2456125 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2456125 | pubmed:pagination | 167-76 | lld:pubmed |
| pubmed-article:2456125 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:2456125 | pubmed:meshHeading | pubmed-meshheading:2456125-... | lld:pubmed |
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| pubmed-article:2456125 | pubmed:meshHeading | pubmed-meshheading:2456125-... | lld:pubmed |
| pubmed-article:2456125 | pubmed:meshHeading | pubmed-meshheading:2456125-... | lld:pubmed |
| pubmed-article:2456125 | pubmed:meshHeading | pubmed-meshheading:2456125-... | lld:pubmed |
| pubmed-article:2456125 | pubmed:meshHeading | pubmed-meshheading:2456125-... | lld:pubmed |
| pubmed-article:2456125 | pubmed:meshHeading | pubmed-meshheading:2456125-... | lld:pubmed |
| pubmed-article:2456125 | pubmed:meshHeading | pubmed-meshheading:2456125-... | lld:pubmed |
| pubmed-article:2456125 | pubmed:year | 1988 | lld:pubmed |
| pubmed-article:2456125 | pubmed:articleTitle | Immunohistochemical evidence for synaptic connections between pro-opiomelanocortin-immunoreactive axons and LH-RH neurons in the preoptic area of the rat. | lld:pubmed |
| pubmed-article:2456125 | pubmed:affiliation | Department of Obstetrics and Gynecology, Yale University School of Medicine, New Haven, CT 06510. | lld:pubmed |
| pubmed-article:2456125 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2456125 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:2456125 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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