| pubmed-article:2453805 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2453805 | lifeskim:mentions | umls-concept:C0034361 | lld:lifeskim |
| pubmed-article:2453805 | lifeskim:mentions | umls-concept:C0220781 | lld:lifeskim |
| pubmed-article:2453805 | lifeskim:mentions | umls-concept:C1883254 | lld:lifeskim |
| pubmed-article:2453805 | lifeskim:mentions | umls-concept:C1515655 | lld:lifeskim |
| pubmed-article:2453805 | lifeskim:mentions | umls-concept:C0073435 | lld:lifeskim |
| pubmed-article:2453805 | pubmed:issue | 6172 | lld:pubmed |
| pubmed-article:2453805 | pubmed:dateCreated | 1988-7-1 | lld:pubmed |
| pubmed-article:2453805 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2453805 | pubmed:abstractText | A variety of small RNAs ranging from tens to hundreds of nucleotides in length grow autocatalytically in a Q beta replicase (Q beta phage RNA-dependent RNA polymerase) reaction in the absence of added template, and similar RNAs are found in Q beta phage-infected Escherichia coli cells. Three such RNAs have been sequenced. One of them that is 221 nucleotides (nt) long ('MDV-1' RNA) has been found to be partially homologous to Q beta phage RNA 8, which might be considered as an indication of its origination from by-products of the Q beta RNA replication. To gain further insight into the origin and function of these RNAs, we have sequenced a new RNA, 120 nt long, isolated from the products of spontaneous synthesis by the nominally RNA-free Q beta replicase preparation. The minus strand of this RNA appeared to be a recombinant RNA, composed of the internal fragment of Q beta RNA (approximately 80 nt long) and the 33-nt-long 3'-terminal fragment of E. coli tRNA(1Asp). This seems to be the first strong indication of RNA recombination in bacterial cells. The various implications of this finding are discussed. | lld:pubmed |
| pubmed-article:2453805 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2453805 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2453805 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2453805 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:2453805 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2453805 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:2453805 | pubmed:issn | 0028-0836 | lld:pubmed |
| pubmed-article:2453805 | pubmed:author | pubmed-author:ChetverinA... | lld:pubmed |
| pubmed-article:2453805 | pubmed:author | pubmed-author:VoroninL ALA | lld:pubmed |
| pubmed-article:2453805 | pubmed:author | pubmed-author:MunishkinA... | lld:pubmed |
| pubmed-article:2453805 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2453805 | pubmed:day | 2 | lld:pubmed |
| pubmed-article:2453805 | pubmed:volume | 333 | lld:pubmed |
| pubmed-article:2453805 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2453805 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2453805 | pubmed:pagination | 473-5 | lld:pubmed |
| pubmed-article:2453805 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:2453805 | pubmed:year | 1988 | lld:pubmed |
| pubmed-article:2453805 | pubmed:articleTitle | An in vivo recombinant RNA capable of autocatalytic synthesis by Q beta replicase. | lld:pubmed |
| pubmed-article:2453805 | pubmed:affiliation | Institute of Protein Research, Academy of Sciences of the USSR, Pushchino, Moscow Region. | lld:pubmed |
| pubmed-article:2453805 | pubmed:publicationType | Journal Article | lld:pubmed |
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