| pubmed-article:2446900 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2446900 | lifeskim:mentions | umls-concept:C0000742 | lld:lifeskim |
| pubmed-article:2446900 | lifeskim:mentions | umls-concept:C0038250 | lld:lifeskim |
| pubmed-article:2446900 | lifeskim:mentions | umls-concept:C0007601 | lld:lifeskim |
| pubmed-article:2446900 | lifeskim:mentions | umls-concept:C0439158 | lld:lifeskim |
| pubmed-article:2446900 | lifeskim:mentions | umls-concept:C0332256 | lld:lifeskim |
| pubmed-article:2446900 | lifeskim:mentions | umls-concept:C0337026 | lld:lifeskim |
| pubmed-article:2446900 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:2446900 | pubmed:dateCreated | 1988-1-27 | lld:pubmed |
| pubmed-article:2446900 | pubmed:abstractText | We have established an in vitro system with which to examine the ability of Abelson murine leukemia virus (A-MuLV) to infect early hemopoietic progenitor cells. Blast cell colonies containing less than 100 cells were shown to contain up to 85% of cells with secondary hemopoietic colony-forming ability. Infection of cells from these blast colonies resulted in generation of transformed mast cell lines when a feeder was provided. Morphological examination of cells taken from infected cultures at various times postinfection indicated a progression of cellular differentiation to the mast cell lineage. Southern analysis on early subclones of transformed cells from two wells, using a v-abl specific probe, indicated a unique pattern of viral integration amongst subclones, suggesting that all subclones had derived from a single cell in each well. Similar results were observed with helper-free Abelson virus obtained by transfecting psi 2 cells with P160 A-MuLV proviral DNA. These data indicate that hemopoietic progenitor cells can be infected by A-MuLV and subsequently in our in vitro culture condition give rise to transformed mast cell lines. | lld:pubmed |
| pubmed-article:2446900 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2446900 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2446900 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2446900 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2446900 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2446900 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:2446900 | pubmed:issn | 0301-472X | lld:pubmed |
| pubmed-article:2446900 | pubmed:author | pubmed-author:NienhuisA WAW | lld:pubmed |
| pubmed-article:2446900 | pubmed:author | pubmed-author:EavesC JCJ | lld:pubmed |
| pubmed-article:2446900 | pubmed:author | pubmed-author:ChengC WCW | lld:pubmed |
| pubmed-article:2446900 | pubmed:author | pubmed-author:WongP MPM | lld:pubmed |
| pubmed-article:2446900 | pubmed:author | pubmed-author:RaefskyEE | lld:pubmed |
| pubmed-article:2446900 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2446900 | pubmed:volume | 16 | lld:pubmed |
| pubmed-article:2446900 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2446900 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2446900 | pubmed:pagination | 5-11 | lld:pubmed |
| pubmed-article:2446900 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:2446900 | pubmed:meshHeading | pubmed-meshheading:2446900-... | lld:pubmed |
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| pubmed-article:2446900 | pubmed:meshHeading | pubmed-meshheading:2446900-... | lld:pubmed |
| pubmed-article:2446900 | pubmed:meshHeading | pubmed-meshheading:2446900-... | lld:pubmed |
| pubmed-article:2446900 | pubmed:meshHeading | pubmed-meshheading:2446900-... | lld:pubmed |
| pubmed-article:2446900 | pubmed:meshHeading | pubmed-meshheading:2446900-... | lld:pubmed |
| pubmed-article:2446900 | pubmed:meshHeading | pubmed-meshheading:2446900-... | lld:pubmed |
| pubmed-article:2446900 | pubmed:meshHeading | pubmed-meshheading:2446900-... | lld:pubmed |
| pubmed-article:2446900 | pubmed:meshHeading | pubmed-meshheading:2446900-... | lld:pubmed |
| pubmed-article:2446900 | pubmed:meshHeading | pubmed-meshheading:2446900-... | lld:pubmed |
| pubmed-article:2446900 | pubmed:meshHeading | pubmed-meshheading:2446900-... | lld:pubmed |
| pubmed-article:2446900 | pubmed:meshHeading | pubmed-meshheading:2446900-... | lld:pubmed |
| pubmed-article:2446900 | pubmed:year | 1988 | lld:pubmed |
| pubmed-article:2446900 | pubmed:articleTitle | Blast colonies containing hemopoietic progenitor cells can give rise to Abelson virus (A-MuLV)-transformed cell lines. | lld:pubmed |
| pubmed-article:2446900 | pubmed:affiliation | Clinical Hematology Branch, National Heart, Lung and Blood Institute, Bethesda, MD 20892. | lld:pubmed |
| pubmed-article:2446900 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2446900 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:2446900 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2446900 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2446900 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2446900 | lld:pubmed |
