| pubmed-article:2439605 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2439605 | lifeskim:mentions | umls-concept:C0012634 | lld:lifeskim |
| pubmed-article:2439605 | lifeskim:mentions | umls-concept:C0022567 | lld:lifeskim |
| pubmed-article:2439605 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:2439605 | lifeskim:mentions | umls-concept:C0443199 | lld:lifeskim |
| pubmed-article:2439605 | lifeskim:mentions | umls-concept:C0456387 | lld:lifeskim |
| pubmed-article:2439605 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:2439605 | lifeskim:mentions | umls-concept:C0002131 | lld:lifeskim |
| pubmed-article:2439605 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:2439605 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:2439605 | pubmed:dateCreated | 1987-7-28 | lld:pubmed |
| pubmed-article:2439605 | pubmed:abstractText | The purpose of this study was to determine whether keratinocytes in certain disease states such as cutaneous T-cell lymphoma and lichen planus, express HLA-DR antigens (corresponding to the murine I-E antigens) only or whether they are also capable of expressing HLA-DQ antigens (analogues of the murine I-A antigens). Cryostat sections from 11 biopsies from cutaneous T-cell lymphoma and from 11 lichen planus biopsy specimens were submitted to indirect immunofluorescence and a 4-step immunoperoxidase method. This consists of applying monoclonal antibodies recognizing HLA-DR and HLA-DQ molecules and the intracytoplasmic invariant chain of the class II molecules. In 8 of the 11 cutaneous T-cell lymphoma specimens and in 3 of the 11 lichen planus biopsies concomitant expression of HLA-DR and HLA-DQ molecules by keratinocytes was detectable with the immunoperoxidase method. However, with the indirect immunofluorescence technique HLA-DQ antigens on keratinocytes could not be detected. The simultaneous expression of surface-bound HLA-DR antigens and intracytoplasmic gamma-chains was demonstrable in all cases investigated and with both the immunohistologic methods applied. | lld:pubmed |
| pubmed-article:2439605 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2439605 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2439605 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2439605 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2439605 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2439605 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2439605 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2439605 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2439605 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:2439605 | pubmed:issn | 0022-202X | lld:pubmed |
| pubmed-article:2439605 | pubmed:author | pubmed-author:GrofPP | lld:pubmed |
| pubmed-article:2439605 | pubmed:author | pubmed-author:WolffKK | lld:pubmed |
| pubmed-article:2439605 | pubmed:author | pubmed-author:Volc-PlatzerB... | lld:pubmed |
| pubmed-article:2439605 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2439605 | pubmed:volume | 89 | lld:pubmed |
| pubmed-article:2439605 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2439605 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2439605 | pubmed:pagination | 64-8 | lld:pubmed |
| pubmed-article:2439605 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:2439605 | pubmed:meshHeading | pubmed-meshheading:2439605-... | lld:pubmed |
| pubmed-article:2439605 | pubmed:meshHeading | pubmed-meshheading:2439605-... | lld:pubmed |
| pubmed-article:2439605 | pubmed:meshHeading | pubmed-meshheading:2439605-... | lld:pubmed |
| pubmed-article:2439605 | pubmed:meshHeading | pubmed-meshheading:2439605-... | lld:pubmed |
| pubmed-article:2439605 | pubmed:meshHeading | pubmed-meshheading:2439605-... | lld:pubmed |
| pubmed-article:2439605 | pubmed:meshHeading | pubmed-meshheading:2439605-... | lld:pubmed |
| pubmed-article:2439605 | pubmed:meshHeading | pubmed-meshheading:2439605-... | lld:pubmed |
| pubmed-article:2439605 | pubmed:meshHeading | pubmed-meshheading:2439605-... | lld:pubmed |
| pubmed-article:2439605 | pubmed:meshHeading | pubmed-meshheading:2439605-... | lld:pubmed |
| pubmed-article:2439605 | pubmed:meshHeading | pubmed-meshheading:2439605-... | lld:pubmed |
| pubmed-article:2439605 | pubmed:meshHeading | pubmed-meshheading:2439605-... | lld:pubmed |
| pubmed-article:2439605 | pubmed:meshHeading | pubmed-meshheading:2439605-... | lld:pubmed |
| pubmed-article:2439605 | pubmed:year | 1987 | lld:pubmed |
| pubmed-article:2439605 | pubmed:articleTitle | Differential expression of class II alloantigens by keratinocytes in disease. | lld:pubmed |
| pubmed-article:2439605 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2439605 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2439605 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2439605 | lld:pubmed |
