| pubmed-article:2420648 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2420648 | lifeskim:mentions | umls-concept:C0151779 | lld:lifeskim |
| pubmed-article:2420648 | lifeskim:mentions | umls-concept:C0232338 | lld:lifeskim |
| pubmed-article:2420648 | lifeskim:mentions | umls-concept:C0554756 | lld:lifeskim |
| pubmed-article:2420648 | lifeskim:mentions | umls-concept:C0162461 | lld:lifeskim |
| pubmed-article:2420648 | lifeskim:mentions | umls-concept:C0237881 | lld:lifeskim |
| pubmed-article:2420648 | lifeskim:mentions | umls-concept:C0750502 | lld:lifeskim |
| pubmed-article:2420648 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:2420648 | pubmed:dateCreated | 1986-5-9 | lld:pubmed |
| pubmed-article:2420648 | pubmed:abstractText | The vascularity of malignant melanoma has been studied in 23 patients by Doppler ultrasonic frequency shift recordings. A 10 or 8 MHz directional Doppler probe was used and the signals were analysed on an Angioscan II spectrum analyser. No blood flow was detected in 7 primary melanomas each of thickness less than 0.75 mm and one recurrent subcutaneous nodule. Abnormal blood flow signals were detected in 8 primary melanomas--each of thickness greater than 1.2 mm--and in 7 skin nodules of secondary melanoma. Three tumours did not conform to the general pattern--one primary tumour 0.7 mm thick had abnormal blood flow signals whereas one primary lesion of 2 mm thickness and one secondary deposit were flow negative. Thus neovascularization corresponds in general to the cut-off point for good prognostic tumours, suggesting that it is a development of biological significance. This vascular pattern can be detected non-invasively by means of a Doppler probe and may have a prognostic importance, particularly with melanomas of the intermediate thickness range of 0.75-3.0 mm, where precise outcome cannot at present be predicted. The significance of an abnormal blood flow in one thin tumour remains to be determined from long-term follow-up. | lld:pubmed |
| pubmed-article:2420648 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2420648 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2420648 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2420648 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2420648 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:2420648 | pubmed:issn | 0748-7983 | lld:pubmed |
| pubmed-article:2420648 | pubmed:author | pubmed-author:HughesL ELE | lld:pubmed |
| pubmed-article:2420648 | pubmed:author | pubmed-author:SrivastavaAA | lld:pubmed |
| pubmed-article:2420648 | pubmed:author | pubmed-author:WoodcockJ PJP | lld:pubmed |
| pubmed-article:2420648 | pubmed:author | pubmed-author:SheddenE JEJ | lld:pubmed |
| pubmed-article:2420648 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2420648 | pubmed:volume | 12 | lld:pubmed |
| pubmed-article:2420648 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2420648 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2420648 | pubmed:pagination | 13-8 | lld:pubmed |
| pubmed-article:2420648 | pubmed:dateRevised | 2007-7-2 | lld:pubmed |
| pubmed-article:2420648 | pubmed:meshHeading | pubmed-meshheading:2420648-... | lld:pubmed |
| pubmed-article:2420648 | pubmed:meshHeading | pubmed-meshheading:2420648-... | lld:pubmed |
| pubmed-article:2420648 | pubmed:meshHeading | pubmed-meshheading:2420648-... | lld:pubmed |
| pubmed-article:2420648 | pubmed:meshHeading | pubmed-meshheading:2420648-... | lld:pubmed |
| pubmed-article:2420648 | pubmed:meshHeading | pubmed-meshheading:2420648-... | lld:pubmed |
| pubmed-article:2420648 | pubmed:meshHeading | pubmed-meshheading:2420648-... | lld:pubmed |
| pubmed-article:2420648 | pubmed:meshHeading | pubmed-meshheading:2420648-... | lld:pubmed |
| pubmed-article:2420648 | pubmed:meshHeading | pubmed-meshheading:2420648-... | lld:pubmed |
| pubmed-article:2420648 | pubmed:meshHeading | pubmed-meshheading:2420648-... | lld:pubmed |
| pubmed-article:2420648 | pubmed:year | 1986 | lld:pubmed |
| pubmed-article:2420648 | pubmed:articleTitle | The significance of blood flow in cutaneous malignant melanoma demonstrated by Doppler flowmetry. | lld:pubmed |
| pubmed-article:2420648 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2420648 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2420648 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2420648 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2420648 | lld:pubmed |
