| pubmed-article:2405695 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2405695 | lifeskim:mentions | umls-concept:C0015688 | lld:lifeskim |
| pubmed-article:2405695 | lifeskim:mentions | umls-concept:C0242485 | lld:lifeskim |
| pubmed-article:2405695 | lifeskim:mentions | umls-concept:C0243127 | lld:lifeskim |
| pubmed-article:2405695 | lifeskim:mentions | umls-concept:C0443331 | lld:lifeskim |
| pubmed-article:2405695 | pubmed:issue | 1 Pt 1 | lld:pubmed |
| pubmed-article:2405695 | pubmed:dateCreated | 1990-3-1 | lld:pubmed |
| pubmed-article:2405695 | pubmed:abstractText | The accuracy of non-steady-state equations for measuring changes in free fatty acid rate of appearance (Ra) is unknown. In the present study, endogenous lipolysis (traced with [14C]-linoleate) was pharmacologically suppressed in six conscious mongrel dogs. A computer-responsive infusion pump was then used to deliver an intravenous oleic acid emulsion in both constant and linear gradient infusion modes. Both non-steady-state equations with various effective volumes of distribution (V) and steady-state equations were used to measure oleate Ra [( 14C]oleate). Endogenous lipolysis did not change during the experiment. When oleate Ra increased in a linear gradient fashion, only non-steady-state equations with a large (150 ml/kg) V resulted in erroneous values (9% overestimate, P less than 0.05). In contrast, when oleate Ra decreased in a similar fashion, steady-state and standard non-steady-state equations (V = plasma volume = 50 ml/kg) overestimated total oleate Ra (18 and 7%, P less than 0.001 and P less than 0.05, respectively). Overall, non-steady-state equations with an effective V of 90 ml/kg (1.8 x plasma volume) allowed the most accurate estimates of oleate Ra. | lld:pubmed |
| pubmed-article:2405695 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2405695 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2405695 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2405695 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2405695 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2405695 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2405695 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2405695 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2405695 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2405695 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2405695 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2405695 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2405695 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2405695 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2405695 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:2405695 | pubmed:issn | 0002-9513 | lld:pubmed |
| pubmed-article:2405695 | pubmed:author | pubmed-author:JensenM DMD | lld:pubmed |
| pubmed-article:2405695 | pubmed:author | pubmed-author:MilesJ MJM | lld:pubmed |
| pubmed-article:2405695 | pubmed:author | pubmed-author:HeilingVV | lld:pubmed |
| pubmed-article:2405695 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2405695 | pubmed:volume | 258 | lld:pubmed |
| pubmed-article:2405695 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2405695 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2405695 | pubmed:pagination | E103-8 | lld:pubmed |
| pubmed-article:2405695 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:2405695 | pubmed:meshHeading | pubmed-meshheading:2405695-... | lld:pubmed |
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| pubmed-article:2405695 | pubmed:meshHeading | pubmed-meshheading:2405695-... | lld:pubmed |
| pubmed-article:2405695 | pubmed:meshHeading | pubmed-meshheading:2405695-... | lld:pubmed |
| pubmed-article:2405695 | pubmed:meshHeading | pubmed-meshheading:2405695-... | lld:pubmed |
| pubmed-article:2405695 | pubmed:meshHeading | pubmed-meshheading:2405695-... | lld:pubmed |
| pubmed-article:2405695 | pubmed:year | 1990 | lld:pubmed |
| pubmed-article:2405695 | pubmed:articleTitle | Measurement of non-steady-state free fatty acid turnover. | lld:pubmed |
| pubmed-article:2405695 | pubmed:affiliation | Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota 55905. | lld:pubmed |
| pubmed-article:2405695 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2405695 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:2405695 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2405695 | lld:pubmed |
