| pubmed-article:2404253 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2404253 | lifeskim:mentions | umls-concept:C0008059 | lld:lifeskim |
| pubmed-article:2404253 | lifeskim:mentions | umls-concept:C0001782 | lld:lifeskim |
| pubmed-article:2404253 | lifeskim:mentions | umls-concept:C0080103 | lld:lifeskim |
| pubmed-article:2404253 | lifeskim:mentions | umls-concept:C0229671 | lld:lifeskim |
| pubmed-article:2404253 | lifeskim:mentions | umls-concept:C0026691 | lld:lifeskim |
| pubmed-article:2404253 | lifeskim:mentions | umls-concept:C0003241 | lld:lifeskim |
| pubmed-article:2404253 | lifeskim:mentions | umls-concept:C1511790 | lld:lifeskim |
| pubmed-article:2404253 | lifeskim:mentions | umls-concept:C1510438 | lld:lifeskim |
| pubmed-article:2404253 | lifeskim:mentions | umls-concept:C0059545 | lld:lifeskim |
| pubmed-article:2404253 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:2404253 | pubmed:dateCreated | 1990-2-12 | lld:pubmed |
| pubmed-article:2404253 | pubmed:abstractText | We describe a new method to measure human serum antibody against streptococcal erythrogenic toxins that uses inhibition of lymphocyte mitogenicity of the toxins as the indicator. Sera from 53% of 53 Kawasaki disease patients contained specific inhibitory activity against A toxin, whereas only 15% had serum inhibitory activity against B toxin. The specific anti-A toxin serum inhibitor was found in 10% of 118 age-matched control patients suffering from various infections and allergic diseases (p = 0.001, compared to Kawasaki disease patients). Serum inhibitory activity was detected in a small number of patients with beta-hemolytic streptococcal infection (3/19) and in none of the age-matched healthy children (0/17). However, four of seven cord blood sera samples and five of 13 sera samples from healthy neonates contained the inhibitor, a result suggesting passive transfer from mothers. Most of the antimitogen-positive sera were also positive by ELISA of IgG antibody against A toxin, and IgG fractions of the positive sera remained positive in both assays. Thus, it is possible that the specific serum inhibitor detected by the antimitogen assay represents anti-A toxin antibody. The role of toxin-producing bacteria in the pathogenesis of Kawasaki disease remains to be investigated. | lld:pubmed |
| pubmed-article:2404253 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2404253 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2404253 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2404253 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2404253 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2404253 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2404253 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2404253 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2404253 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2404253 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2404253 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2404253 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2404253 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:2404253 | pubmed:issn | 0031-3998 | lld:pubmed |
| pubmed-article:2404253 | pubmed:author | pubmed-author:NomaSS | lld:pubmed |
| pubmed-article:2404253 | pubmed:author | pubmed-author:ItoSS | lld:pubmed |
| pubmed-article:2404253 | pubmed:author | pubmed-author:AbeYY | lld:pubmed |
| pubmed-article:2404253 | pubmed:author | pubmed-author:NakaharaTT | lld:pubmed |
| pubmed-article:2404253 | pubmed:author | pubmed-author:YoshinoKK | lld:pubmed |
| pubmed-article:2404253 | pubmed:author | pubmed-author:NakanoSS | lld:pubmed |
| pubmed-article:2404253 | pubmed:author | pubmed-author:KatzDD | lld:pubmed |
| pubmed-article:2404253 | pubmed:author | pubmed-author:UshijimaHH | lld:pubmed |
| pubmed-article:2404253 | pubmed:author | pubmed-author:OkitsuSS | lld:pubmed |
| pubmed-article:2404253 | pubmed:author | pubmed-author:KamezawaYY | lld:pubmed |
| pubmed-article:2404253 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2404253 | pubmed:volume | 27 | lld:pubmed |
| pubmed-article:2404253 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2404253 | pubmed:authorsComplete | N | lld:pubmed |
| pubmed-article:2404253 | pubmed:pagination | 11-5 | lld:pubmed |
| pubmed-article:2404253 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:2404253 | pubmed:meshHeading | pubmed-meshheading:2404253-... | lld:pubmed |
| pubmed-article:2404253 | pubmed:meshHeading | pubmed-meshheading:2404253-... | lld:pubmed |
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| pubmed-article:2404253 | pubmed:meshHeading | pubmed-meshheading:2404253-... | lld:pubmed |
| pubmed-article:2404253 | pubmed:meshHeading | pubmed-meshheading:2404253-... | lld:pubmed |
| pubmed-article:2404253 | pubmed:meshHeading | pubmed-meshheading:2404253-... | lld:pubmed |
| pubmed-article:2404253 | pubmed:meshHeading | pubmed-meshheading:2404253-... | lld:pubmed |
| pubmed-article:2404253 | pubmed:meshHeading | pubmed-meshheading:2404253-... | lld:pubmed |
| pubmed-article:2404253 | pubmed:meshHeading | pubmed-meshheading:2404253-... | lld:pubmed |
| pubmed-article:2404253 | pubmed:meshHeading | pubmed-meshheading:2404253-... | lld:pubmed |
| pubmed-article:2404253 | pubmed:meshHeading | pubmed-meshheading:2404253-... | lld:pubmed |
| pubmed-article:2404253 | pubmed:year | 1990 | lld:pubmed |
| pubmed-article:2404253 | pubmed:articleTitle | Detection of serum antibody by the antimitogen assay against streptococcal erythrogenic toxins. Age distribution in children and the relation to Kawasaki disease. | lld:pubmed |
| pubmed-article:2404253 | pubmed:affiliation | Department of Pathology, Teikyo University School of Medicine, Japan. | lld:pubmed |
| pubmed-article:2404253 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2404253 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2404253 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2404253 | lld:pubmed |
