| pubmed-article:2403927 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2403927 | lifeskim:mentions | umls-concept:C0036025 | lld:lifeskim |
| pubmed-article:2403927 | lifeskim:mentions | umls-concept:C0017337 | lld:lifeskim |
| pubmed-article:2403927 | lifeskim:mentions | umls-concept:C0035680 | lld:lifeskim |
| pubmed-article:2403927 | lifeskim:mentions | umls-concept:C1533691 | lld:lifeskim |
| pubmed-article:2403927 | lifeskim:mentions | umls-concept:C1515655 | lld:lifeskim |
| pubmed-article:2403927 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:2403927 | pubmed:dateCreated | 1990-2-21 | lld:pubmed |
| pubmed-article:2403927 | pubmed:abstractText | Unlike the majority of genes encoding small nuclear RNAs, which are transcribed by RNA polymerase B, the U6 gene contains features found in both class B and class C genes, indicating the involvement of a combination of transcription factors normally specific to each class of genes. We present direct genetic and biochemical evidence that the U6 gene of Saccharomyces cerevisiae is transcribed by RNA polymerase C in vivo as well as in vitro. A mutant strain with a temperature-sensitive defect in the large subunit of RNA polymerase C that results in defective transcription of tRNA and 5S RNA genes shows a corresponding defect in U6 RNA levels. Also, purified RNA polymerase C transcribes the U6 gene when supplemented with partially purified TFIIIB. The other class C transcription factors, TFIIIA and Tau (TFIIIC), are not required in this system. | lld:pubmed |
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| pubmed-article:2403927 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2403927 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2403927 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:2403927 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2403927 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:2403927 | pubmed:issn | 0261-4189 | lld:pubmed |
| pubmed-article:2403927 | pubmed:author | pubmed-author:SentenacAA | lld:pubmed |
| pubmed-article:2403927 | pubmed:author | pubmed-author:AndersonGG | lld:pubmed |
| pubmed-article:2403927 | pubmed:author | pubmed-author:CamierSS | lld:pubmed |
| pubmed-article:2403927 | pubmed:author | pubmed-author:MoenneAA | lld:pubmed |
| pubmed-article:2403927 | pubmed:author | pubmed-author:BeggsJJ | lld:pubmed |
| pubmed-article:2403927 | pubmed:author | pubmed-author:MargottinFF | lld:pubmed |
| pubmed-article:2403927 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2403927 | pubmed:volume | 9 | lld:pubmed |
| pubmed-article:2403927 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2403927 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2403927 | pubmed:pagination | 271-7 | lld:pubmed |
| pubmed-article:2403927 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:2403927 | pubmed:year | 1990 | lld:pubmed |
| pubmed-article:2403927 | pubmed:articleTitle | The U6 gene of Saccharomyces cerevisiae is transcribed by RNA polymerase C (III) in vivo and in vitro. | lld:pubmed |
| pubmed-article:2403927 | pubmed:affiliation | Département de Biologie, CEN de Saclay, Commissariat à l'Energie Atomique, Gif sur Yvette, France. | lld:pubmed |
| pubmed-article:2403927 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2403927 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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