| pubmed-article:2403351 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2403351 | lifeskim:mentions | umls-concept:C0034493 | lld:lifeskim |
| pubmed-article:2403351 | lifeskim:mentions | umls-concept:C0003483 | lld:lifeskim |
| pubmed-article:2403351 | lifeskim:mentions | umls-concept:C0039654 | lld:lifeskim |
| pubmed-article:2403351 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:2403351 | lifeskim:mentions | umls-concept:C0070750 | lld:lifeskim |
| pubmed-article:2403351 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:2403351 | pubmed:dateCreated | 1990-10-19 | lld:pubmed |
| pubmed-article:2403351 | pubmed:abstractText | In rat hepatocytes, active phorbol esters inhibited the alpha 1-adrenergic stimulation of phosphatidylinositol labeling with the expected potency order: phorbol myristate acetate (PMA) greater than phorbol dibutyrate (PDB). In contrast, in rabbit aorta the alpha 1-adrenergic action was inhibited dose-dependently by PDB but not by PMA. Similarly PDB (but not PMA) induced a strong contraction in rabbit aorta. The phorbol ester-induced contraction developed slowly, was dose-dependent and independent of extracellular calcium. These effects of PDB in rabbit aorta were neither inhibited by the protein kinase inhibitor H-7 nor mimicked by the synthetic diacylglycerol, OAG. Our results raise some doubts on the mechanism(s) through which the actions of PDB take place in rabbit aorta. | lld:pubmed |
| pubmed-article:2403351 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2403351 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2403351 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2403351 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2403351 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2403351 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2403351 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2403351 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2403351 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2403351 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2403351 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2403351 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2403351 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2403351 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:2403351 | pubmed:issn | 0006-291X | lld:pubmed |
| pubmed-article:2403351 | pubmed:author | pubmed-author:HongEE | lld:pubmed |
| pubmed-article:2403351 | pubmed:author | pubmed-author:García-SáinzJ... | lld:pubmed |
| pubmed-article:2403351 | pubmed:author | pubmed-author:Villalobos-Mo... | lld:pubmed |
| pubmed-article:2403351 | pubmed:author | pubmed-author:RansanzVV | lld:pubmed |
| pubmed-article:2403351 | pubmed:author | pubmed-author:Torres-Márque... | lld:pubmed |
| pubmed-article:2403351 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2403351 | pubmed:day | 14 | lld:pubmed |
| pubmed-article:2403351 | pubmed:volume | 171 | lld:pubmed |
| pubmed-article:2403351 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2403351 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2403351 | pubmed:pagination | 618-24 | lld:pubmed |
| pubmed-article:2403351 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:2403351 | pubmed:meshHeading | pubmed-meshheading:2403351-... | lld:pubmed |
| pubmed-article:2403351 | pubmed:meshHeading | pubmed-meshheading:2403351-... | lld:pubmed |
| pubmed-article:2403351 | pubmed:meshHeading | pubmed-meshheading:2403351-... | lld:pubmed |
| pubmed-article:2403351 | pubmed:meshHeading | pubmed-meshheading:2403351-... | lld:pubmed |
| pubmed-article:2403351 | pubmed:meshHeading | pubmed-meshheading:2403351-... | lld:pubmed |
| pubmed-article:2403351 | pubmed:meshHeading | pubmed-meshheading:2403351-... | lld:pubmed |
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| pubmed-article:2403351 | pubmed:meshHeading | pubmed-meshheading:2403351-... | lld:pubmed |
| pubmed-article:2403351 | pubmed:meshHeading | pubmed-meshheading:2403351-... | lld:pubmed |
| pubmed-article:2403351 | pubmed:meshHeading | pubmed-meshheading:2403351-... | lld:pubmed |
| pubmed-article:2403351 | pubmed:meshHeading | pubmed-meshheading:2403351-... | lld:pubmed |
| pubmed-article:2403351 | pubmed:meshHeading | pubmed-meshheading:2403351-... | lld:pubmed |
| pubmed-article:2403351 | pubmed:meshHeading | pubmed-meshheading:2403351-... | lld:pubmed |
| pubmed-article:2403351 | pubmed:meshHeading | pubmed-meshheading:2403351-... | lld:pubmed |
| pubmed-article:2403351 | pubmed:meshHeading | pubmed-meshheading:2403351-... | lld:pubmed |
| pubmed-article:2403351 | pubmed:year | 1990 | lld:pubmed |
| pubmed-article:2403351 | pubmed:articleTitle | Contrasting effects of phorbol dibutyrate and phorbol myristate acetate in rabbit aorta. | lld:pubmed |
| pubmed-article:2403351 | pubmed:affiliation | Depto. de Farmacología, CINVESTAV-IPN, Mexico, D.F. | lld:pubmed |
| pubmed-article:2403351 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2403351 | pubmed:publicationType | In Vitro | lld:pubmed |
| pubmed-article:2403351 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2403351 | lld:pubmed |
