| pubmed-article:2382724 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2382724 | lifeskim:mentions | umls-concept:C0012984 | lld:lifeskim |
| pubmed-article:2382724 | lifeskim:mentions | umls-concept:C0934502 | lld:lifeskim |
| pubmed-article:2382724 | lifeskim:mentions | umls-concept:C0009368 | lld:lifeskim |
| pubmed-article:2382724 | lifeskim:mentions | umls-concept:C0678544 | lld:lifeskim |
| pubmed-article:2382724 | lifeskim:mentions | umls-concept:C0205148 | lld:lifeskim |
| pubmed-article:2382724 | lifeskim:mentions | umls-concept:C0439834 | lld:lifeskim |
| pubmed-article:2382724 | lifeskim:mentions | umls-concept:C1515025 | lld:lifeskim |
| pubmed-article:2382724 | lifeskim:mentions | umls-concept:C0731521 | lld:lifeskim |
| pubmed-article:2382724 | lifeskim:mentions | umls-concept:C1282913 | lld:lifeskim |
| pubmed-article:2382724 | pubmed:issue | 2 Pt 1 | lld:pubmed |
| pubmed-article:2382724 | pubmed:dateCreated | 1990-9-11 | lld:pubmed |
| pubmed-article:2382724 | pubmed:abstractText | Colonic slow waves originate from pacemaker cells along the submucosal surface of the circular layer in the dog proximal colon. These events propagate in a nonregenerative manner into the bulk of the circular layer. Conduction velocities consistent with an active mechanism for slow-wave propagation in the longitudinal and circumferential axes of the colon have been reported. Experiments were performed using intracellular recording techniques on canine colonic muscles to determine the regenerative pathway for slow-wave propagation. In a thin band of muscle adjacent to the submucosal border of the circular layer, slow-wave amplitude was independent of distance from a pacing source, and events propagated at a rate of approximately 17 mm/s in the long axis of the circular fibers and 6 mm/s in the transverse axis of the circular fibers. These findings suggest that slow waves propagate in a regenerative manner in this region. Slow waves decayed as they conducted through regions from which the pacemaker cells had been removed with space constants of a few millimeters. Thus the integrity of the thin pacemaker region along submucosal surface is critical for propagation of slow waves and the organization of motility into segmental contractions. | lld:pubmed |
| pubmed-article:2382724 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2382724 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2382724 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2382724 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2382724 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2382724 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:2382724 | pubmed:issn | 0002-9513 | lld:pubmed |
| pubmed-article:2382724 | pubmed:author | pubmed-author:BurkeEE | lld:pubmed |
| pubmed-article:2382724 | pubmed:author | pubmed-author:StevensRR | lld:pubmed |
| pubmed-article:2382724 | pubmed:author | pubmed-author:SandersK MKM | lld:pubmed |
| pubmed-article:2382724 | pubmed:author | pubmed-author:WardS WSW | lld:pubmed |
| pubmed-article:2382724 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2382724 | pubmed:volume | 259 | lld:pubmed |
| pubmed-article:2382724 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2382724 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2382724 | pubmed:pagination | G258-63 | lld:pubmed |
| pubmed-article:2382724 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:2382724 | pubmed:meshHeading | pubmed-meshheading:2382724-... | lld:pubmed |
| pubmed-article:2382724 | pubmed:meshHeading | pubmed-meshheading:2382724-... | lld:pubmed |
| pubmed-article:2382724 | pubmed:meshHeading | pubmed-meshheading:2382724-... | lld:pubmed |
| pubmed-article:2382724 | pubmed:meshHeading | pubmed-meshheading:2382724-... | lld:pubmed |
| pubmed-article:2382724 | pubmed:meshHeading | pubmed-meshheading:2382724-... | lld:pubmed |
| pubmed-article:2382724 | pubmed:meshHeading | pubmed-meshheading:2382724-... | lld:pubmed |
| pubmed-article:2382724 | pubmed:meshHeading | pubmed-meshheading:2382724-... | lld:pubmed |
| pubmed-article:2382724 | pubmed:meshHeading | pubmed-meshheading:2382724-... | lld:pubmed |
| pubmed-article:2382724 | pubmed:meshHeading | pubmed-meshheading:2382724-... | lld:pubmed |
| pubmed-article:2382724 | pubmed:meshHeading | pubmed-meshheading:2382724-... | lld:pubmed |
| pubmed-article:2382724 | pubmed:year | 1990 | lld:pubmed |
| pubmed-article:2382724 | pubmed:articleTitle | Slow waves actively propagate at submucosal surface of circular layer in canine colon. | lld:pubmed |
| pubmed-article:2382724 | pubmed:affiliation | Department of Physiology, University of Nevada School of Medicine, Reno 89557. | lld:pubmed |
| pubmed-article:2382724 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2382724 | pubmed:publicationType | In Vitro | lld:pubmed |
| pubmed-article:2382724 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:2382724 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2382724 | lld:pubmed |
