| pubmed-article:2374086 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2374086 | lifeskim:mentions | umls-concept:C0034721 | lld:lifeskim |
| pubmed-article:2374086 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:2374086 | lifeskim:mentions | umls-concept:C1267092 | lld:lifeskim |
| pubmed-article:2374086 | lifeskim:mentions | umls-concept:C0042360 | lld:lifeskim |
| pubmed-article:2374086 | lifeskim:mentions | umls-concept:C0033497 | lld:lifeskim |
| pubmed-article:2374086 | lifeskim:mentions | umls-concept:C0279023 | lld:lifeskim |
| pubmed-article:2374086 | lifeskim:mentions | umls-concept:C1533157 | lld:lifeskim |
| pubmed-article:2374086 | lifeskim:mentions | umls-concept:C1140999 | lld:lifeskim |
| pubmed-article:2374086 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:2374086 | pubmed:dateCreated | 1990-8-30 | lld:pubmed |
| pubmed-article:2374086 | pubmed:abstractText | In the smooth muscle of the rat vas deferens, 10(-5) M cocaine shifted the dose-response curve to norepinephrine to the left and enhanced the maximal contractions to norepinephrine and methacholine. Propranolol at 10(-4) M almost completely blocked these potentiating effects of cocaine. Sotalol or lidocaine at 10(-4) M did not block the potentiating action of cocaine. The cocaine-induced enhancement of the methacholine contraction and its blockade by propranolol was observed in the dibenamine-treated vas deferens. Propranolol also blocked the depolarization-induced enhancement of the methacholine contraction. Together with the previous study demonstrating the calcium-antagonist action for propranolol, these results suggest that propranolol blocks the cocaine-induced enhancement by inhibiting the calcium influx through the potential-dependent calcium channel in the rat vas deferens. | lld:pubmed |
| pubmed-article:2374086 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2374086 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2374086 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2374086 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2374086 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2374086 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2374086 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2374086 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2374086 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:2374086 | pubmed:issn | 0386-846X | lld:pubmed |
| pubmed-article:2374086 | pubmed:author | pubmed-author:OnoKK | lld:pubmed |
| pubmed-article:2374086 | pubmed:author | pubmed-author:KasuyaYY | lld:pubmed |
| pubmed-article:2374086 | pubmed:author | pubmed-author:SuzukiNN | lld:pubmed |
| pubmed-article:2374086 | pubmed:author | pubmed-author:GomiYY | lld:pubmed |
| pubmed-article:2374086 | pubmed:author | pubmed-author:InagakiOO | lld:pubmed |
| pubmed-article:2374086 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2374086 | pubmed:volume | 13 | lld:pubmed |
| pubmed-article:2374086 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2374086 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2374086 | pubmed:pagination | 172-8 | lld:pubmed |
| pubmed-article:2374086 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:2374086 | pubmed:meshHeading | pubmed-meshheading:2374086-... | lld:pubmed |
| pubmed-article:2374086 | pubmed:meshHeading | pubmed-meshheading:2374086-... | lld:pubmed |
| pubmed-article:2374086 | pubmed:meshHeading | pubmed-meshheading:2374086-... | lld:pubmed |
| pubmed-article:2374086 | pubmed:meshHeading | pubmed-meshheading:2374086-... | lld:pubmed |
| pubmed-article:2374086 | pubmed:meshHeading | pubmed-meshheading:2374086-... | lld:pubmed |
| pubmed-article:2374086 | pubmed:meshHeading | pubmed-meshheading:2374086-... | lld:pubmed |
| pubmed-article:2374086 | pubmed:meshHeading | pubmed-meshheading:2374086-... | lld:pubmed |
| pubmed-article:2374086 | pubmed:meshHeading | pubmed-meshheading:2374086-... | lld:pubmed |
| pubmed-article:2374086 | pubmed:meshHeading | pubmed-meshheading:2374086-... | lld:pubmed |
| pubmed-article:2374086 | pubmed:meshHeading | pubmed-meshheading:2374086-... | lld:pubmed |
| pubmed-article:2374086 | pubmed:meshHeading | pubmed-meshheading:2374086-... | lld:pubmed |
| pubmed-article:2374086 | pubmed:meshHeading | pubmed-meshheading:2374086-... | lld:pubmed |
| pubmed-article:2374086 | pubmed:year | 1990 | lld:pubmed |
| pubmed-article:2374086 | pubmed:articleTitle | Propranolol blocks cocaine-induced potentiation of the contraction in the smooth muscle of the rat vas deferens. | lld:pubmed |
| pubmed-article:2374086 | pubmed:affiliation | Department of Pharmacology, Faculty of Pharmaceutical Sciences, Kanazawa University, Japan. | lld:pubmed |
| pubmed-article:2374086 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2374086 | pubmed:publicationType | In Vitro | lld:pubmed |
