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pubmed-article:2367561pubmed:abstractTextRadioimmunoassays were used to investigate the repair of cyclobutane pyrimidine dimers and pyrimidine (6-4)pyrimidone photoproducts ((6-4] photoproducts) in the epidermis of the South American opossum, Monodelphis domestica. In the absence of photoreactivating light, both types of photodamage were excised with similar kinetics, 50% of the damage remaining 8 h after UV irradiation in vivo. Exposure of UV-irradiated skin to photoreactivating light resulted in removal of most of the cyclobutane dimers and an enhanced rate of (6-4) photoproduct repair. Photoenhanced excision repair of non-dimer damage increases the range of biologically effective lesions removed by in vivo photoreactivation.lld:pubmed
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pubmed-article:2367561pubmed:authorpubmed-author:MitchellD LDLlld:pubmed
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pubmed-article:2367561pubmed:dateRevised2007-11-14lld:pubmed
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pubmed-article:2367561pubmed:articleTitlePhotoreactivation of cyclobutane dimers and (6-4) photoproducts in the epidermis of the marsupial, Monodelphis domestica.lld:pubmed
pubmed-article:2367561pubmed:affiliationDepartment of Experimental Carcinogenesis, University of Texas, M.D. Anderson Cancer Center, Smithville 78957.lld:pubmed
pubmed-article:2367561pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:2367561pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
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