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pubmed-article:2355835pubmed:abstractTextIn vivo measurement of cerebral physiology by dynamic contrast-enhanced NMR is demonstrated. Time-resolved images of the cerebral transit of paramagnetic contrast agent were acquired using a new ultrafast NMR imaging technique and a novel mechanism of image contrast based on microscopic changes in tissue magnetic susceptibility. Global hypercapnia in dogs was used to establish the relationship between susceptibility-induced signal change and brain blood volume, and the response of gray and white matter to this microvascular stimulus was measured.lld:pubmed
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pubmed-article:2355835pubmed:articleTitleFunctional cerebral imaging by susceptibility-contrast NMR.lld:pubmed
pubmed-article:2355835pubmed:affiliationDepartment of Radiology, Massachusetts General Hospital, Boston.lld:pubmed
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