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pubmed-article:2340694pubmed:abstractTextAbnormalities on magnetic resonance imaging (MRI) are reported in six individuals with various skeletal complications of type I Gaucher disease. The changes were a nonhomogeneous reduction in both T1 and T2 marrow signals with increased T2 signals during avascular episodes. MRI proved an excellent technique for the assessment of bone marrow changes in Type I Gaucher disease and for assessing avascular complications. It was not able to differentiate between pseudo-osteomyelitis and pyogenic osteomyelitis without clinical correlation. The problems studied included the extent of intramedullary Gaucher cell infiltration, avascular necrosis of femoral heads, assessment of bone pain from pseudo-osteomyelitis and the relationship of skeletal disease to splenectomy.lld:pubmed
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pubmed-article:2340694pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:2340694pubmed:year1990lld:pubmed
pubmed-article:2340694pubmed:articleTitleSkeletal complications of type I Gaucher disease: the magnetic resonance features.lld:pubmed
pubmed-article:2340694pubmed:affiliationPaediatric Radiology, Red Cross Children's Hospital, University of Cape Town, South Africa.lld:pubmed
pubmed-article:2340694pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:2340694pubmed:publicationTypeCase Reportslld:pubmed
pubmed-article:2340694pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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