pubmed-article:2321906 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:2321906 | lifeskim:mentions | umls-concept:C0087111 | lld:lifeskim |
pubmed-article:2321906 | lifeskim:mentions | umls-concept:C0010690 | lld:lifeskim |
pubmed-article:2321906 | lifeskim:mentions | umls-concept:C0010648 | lld:lifeskim |
pubmed-article:2321906 | pubmed:issue | 2 | lld:pubmed |
pubmed-article:2321906 | pubmed:dateCreated | 1990-5-10 | lld:pubmed |
pubmed-article:2321906 | pubmed:abstractText | Eighteen pediatric patients with cystinosis were treated with cysteamine. Treatment was started at a variable age, between 10 months and 7 years, and was continued for 6 months to eight years. Results were evaluated on renal function changes and growth. Whereas 65% of patients with cystinosis develop terminal renal failure before the age of ten years, three (16%) of our 18 patients given cysteamine started dialysis before the age of ten and all three had first received cysteamine only after 4 1/2 years of age. The plasma creatinine level was also lower in treated patients as compared with a control multicenter group. Growth was also significantly improved by treatment, especially in those children treated before the age of 26 months who were taller by 2 SD at age five and 2.5 SD at age eight than untreated controls. Some children who complied strictly with the treatment regimen had an normal stature (- 1 SD) at ten years of age. In conclusion, the effectiveness of cysteamine seems obvious in this group of patients if rigorous compliance with the drug dosing schedule is achieved. | lld:pubmed |
pubmed-article:2321906 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2321906 | pubmed:language | fre | lld:pubmed |
pubmed-article:2321906 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2321906 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:2321906 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2321906 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2321906 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:2321906 | pubmed:month | Feb | lld:pubmed |
pubmed-article:2321906 | pubmed:issn | 0066-2097 | lld:pubmed |
pubmed-article:2321906 | pubmed:author | pubmed-author:BroyerMM | lld:pubmed |
pubmed-article:2321906 | pubmed:author | pubmed-author:TeteM JMJ | lld:pubmed |
pubmed-article:2321906 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:2321906 | pubmed:volume | 37 | lld:pubmed |
pubmed-article:2321906 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:2321906 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:2321906 | pubmed:pagination | 91-3 | lld:pubmed |
pubmed-article:2321906 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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pubmed-article:2321906 | pubmed:year | 1990 | lld:pubmed |
pubmed-article:2321906 | pubmed:articleTitle | [Treatment of cystinosis using cysteamine]. | lld:pubmed |
pubmed-article:2321906 | pubmed:affiliation | Service de Néphrologie Pédiatrique, Hôpital des Enfants-Malades, Paris. | lld:pubmed |
pubmed-article:2321906 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:2321906 | pubmed:publicationType | English Abstract | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2321906 | lld:pubmed |