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pubmed-article:2290621pubmed:abstractTextRecovery of Schwann cell-neuronal interactions altered by suppression of endogenous nerve growth factor (NGF) with antibodies to NGF (anti-NGF) was determined by morphometric analysis of unmyelinated and myelinated sensory fibers in the T9 dorsal roots in 3 groups of animals: (1) rats one week after cessation of anti-NGF treatment (anti-NGF + 1WK), (2) rats given antibodies to NGF (anti-NGF) and (3) untreated same age littermates (UNTR). The results indicate that (1) recovery of normal myelination begins within one week of cessation of anti-NGF treatment for small caliber fibers and (2) the observed results of anti-NGF treatment on Schwann cell-neuronal interactions were due to anti-NGF treatment and were not an indirect effect of a general diseased state.lld:pubmed
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pubmed-article:2290621pubmed:articleTitleIn vivo recovery of Schwann cell-neuronal interactions altered by nerve growth factor suppression in the rat.lld:pubmed
pubmed-article:2290621pubmed:affiliationDepartment of Anatomy and Neurosciences, University of Texas Medical Branch, Galveston 77550-2772.lld:pubmed
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