pubmed-article:2282185 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:2282185 | lifeskim:mentions | umls-concept:C0019704 | lld:lifeskim |
pubmed-article:2282185 | lifeskim:mentions | umls-concept:C0024109 | lld:lifeskim |
pubmed-article:2282185 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
pubmed-article:2282185 | lifeskim:mentions | umls-concept:C0024432 | lld:lifeskim |
pubmed-article:2282185 | lifeskim:mentions | umls-concept:C1511790 | lld:lifeskim |
pubmed-article:2282185 | lifeskim:mentions | umls-concept:C0032520 | lld:lifeskim |
pubmed-article:2282185 | pubmed:issue | 11 | lld:pubmed |
pubmed-article:2282185 | pubmed:dateCreated | 1991-3-21 | lld:pubmed |
pubmed-article:2282185 | pubmed:abstractText | We have used the polymerase chain reaction to investigate HIV-1 infection of lung macrophages from 44 AIDS patients with pneumonia. Proviral HIV-1 DNA was detected in the lung macrophages of 47% (21 of 44) of patients tested; 32% (seven of 21) of the patients had Pneumocystis carinii pneumonia (PCP), and 56% (11 of 21) had pneumonia caused by other aetiological agents. Matched peripheral blood specimens were obtained from 22 patients in this study, and HIV-1-specific DNA was detected in 100% (22 out of 22) of non-adherent white cell preparations tested. HIV was detected in blood monocytes of 11 out of 22 patients (50%), and a virus signal was also found in the lung macrophages of eight of these patients. Our results indicate that PCP does not predispose lung macrophages to HIV-1, nor does HIV-1 infection of lung macrophages increase the probability of contracting PCP. | lld:pubmed |
pubmed-article:2282185 | pubmed:language | eng | lld:pubmed |
pubmed-article:2282185 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2282185 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:2282185 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2282185 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:2282185 | pubmed:month | Nov | lld:pubmed |
pubmed-article:2282185 | pubmed:issn | 0269-9370 | lld:pubmed |
pubmed-article:2282185 | pubmed:author | pubmed-author:MitchellDD | lld:pubmed |
pubmed-article:2282185 | pubmed:author | pubmed-author:JeffriesD JDJ | lld:pubmed |
pubmed-article:2282185 | pubmed:author | pubmed-author:BennettJJ | lld:pubmed |
pubmed-article:2282185 | pubmed:author | pubmed-author:KrishnanVV | lld:pubmed |
pubmed-article:2282185 | pubmed:author | pubmed-author:ClarkeJ RJR | lld:pubmed |
pubmed-article:2282185 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:2282185 | pubmed:volume | 4 | lld:pubmed |
pubmed-article:2282185 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:2282185 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:2282185 | pubmed:pagination | 1133-6 | lld:pubmed |
pubmed-article:2282185 | pubmed:dateRevised | 2004-11-17 | lld:pubmed |
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pubmed-article:2282185 | pubmed:year | 1990 | lld:pubmed |
pubmed-article:2282185 | pubmed:articleTitle | Detection of HIV-1 in human lung macrophages using the polymerase chain reaction. | lld:pubmed |
pubmed-article:2282185 | pubmed:affiliation | Department of Medical Microbiology, St Mary's Hospital Medical School, London, UK. | lld:pubmed |
pubmed-article:2282185 | pubmed:publicationType | Journal Article | lld:pubmed |
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