pubmed-article:2278087 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:2278087 | lifeskim:mentions | umls-concept:C0016832 | lld:lifeskim |
pubmed-article:2278087 | lifeskim:mentions | umls-concept:C0043393 | lld:lifeskim |
pubmed-article:2278087 | lifeskim:mentions | umls-concept:C0038033 | lld:lifeskim |
pubmed-article:2278087 | lifeskim:mentions | umls-concept:C0003250 | lld:lifeskim |
pubmed-article:2278087 | lifeskim:mentions | umls-concept:C0205390 | lld:lifeskim |
pubmed-article:2278087 | lifeskim:mentions | umls-concept:C1521827 | lld:lifeskim |
pubmed-article:2278087 | lifeskim:mentions | umls-concept:C0591833 | lld:lifeskim |
pubmed-article:2278087 | pubmed:issue | 5 | lld:pubmed |
pubmed-article:2278087 | pubmed:dateCreated | 1991-3-1 | lld:pubmed |
pubmed-article:2278087 | pubmed:abstractText | Three murine monoclonal antibodies (Mabs) were raised against a cytoplasmic antigen of the yeast phase of the pathogenic fungus Sporothrix schenckii using a modification of standard hybridoma technology incorporating the immunosuppressive drug cyclophosphamide. When tested for species-specificity within the pathogenic dimorphic fungi one of these Mabs (S5) showed little cross-reactivity by enzyme-linked immunosorbent assay and Western blot, though there was some recognition of Paracoccidioides brasiliensis antigen. This Mab recognized a 70-75 kDa molecule on reduced Western blots of S. schenckii antigen. The other two Mabs (S12 and S15) showed cross-reactivity with all dimorphic fungal antigens tested, though they appeared to recognize a molecule of similar molecular weight. This is the first report of any attempt to raise species-specific Mabs against this important causative agent of dermatological disease. | lld:pubmed |
pubmed-article:2278087 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2278087 | pubmed:language | eng | lld:pubmed |
pubmed-article:2278087 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2278087 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:2278087 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2278087 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2278087 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:2278087 | pubmed:issn | 0035-9203 | lld:pubmed |
pubmed-article:2278087 | pubmed:author | pubmed-author:HaradaTT | lld:pubmed |
pubmed-article:2278087 | pubmed:author | pubmed-author:HayR JRJ | lld:pubmed |
pubmed-article:2278087 | pubmed:author | pubmed-author:HamiltonA JAJ | lld:pubmed |
pubmed-article:2278087 | pubmed:author | pubmed-author:BartholomewM... | lld:pubmed |
pubmed-article:2278087 | pubmed:author | pubmed-author:FigueroaJ IJI | lld:pubmed |
pubmed-article:2278087 | pubmed:author | pubmed-author:FenelonLL | lld:pubmed |
pubmed-article:2278087 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:2278087 | pubmed:volume | 84 | lld:pubmed |
pubmed-article:2278087 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:2278087 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:2278087 | pubmed:pagination | 734-7 | lld:pubmed |
pubmed-article:2278087 | pubmed:dateRevised | 2009-9-29 | lld:pubmed |
pubmed-article:2278087 | pubmed:meshHeading | pubmed-meshheading:2278087-... | lld:pubmed |
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pubmed-article:2278087 | pubmed:meshHeading | pubmed-meshheading:2278087-... | lld:pubmed |
pubmed-article:2278087 | pubmed:articleTitle | Preparation of murine monoclonal antibodies against the yeast phase of the dimorphic fungus Sporothrix schenckii. | lld:pubmed |
pubmed-article:2278087 | pubmed:affiliation | Department of Clinical Sciences, Guy's Hospital, London Bridge, UK. | lld:pubmed |
pubmed-article:2278087 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:2278087 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |