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pubmed-article:22073049rdf:typepubmed:Citationlld:pubmed
pubmed-article:22073049lifeskim:mentionsumls-concept:C0260662lld:lifeskim
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pubmed-article:22073049lifeskim:mentionsumls-concept:C0184661lld:lifeskim
pubmed-article:22073049pubmed:dateCreated2011-11-10lld:pubmed
pubmed-article:22073049pubmed:abstractTextA wide range of therapeutic strategies are available for the therapy of hearing disorders including pharmaceutical, acoustic, electrical, surgical, radiological, cognitive-behavioural and so-called "alternative" strategies. This review focuses on general conservative strategies and specific therapeutic approaches mainly for inner ear disorders, whereas surgical and device-based therapies including hearing aids and cochlear implants are described in other chapters in this volume.In addition to the systemic medication-based therapies for the treatment of hearing disorders, the rapidly growing field of local drug delivery to the inner ear as a promising therapeutic strategy is discussed on the background of unresolved issues. After description of non-drug-based therapeutic procedures, the conservative therapy of specific diseases and syndromes is reviewed.In general, there is a major discrepancy between promising animal studies up to regeneration and stem-cell transplantation, and uncontrolled experimental studies in humans on the one hand and the shortage of randomized controlled clinical trials with a high level of evidence on the other hand. Therefore, the review and comments on published clinical studies should assist the reader in making his/her own decision about the effectiveness of various, especially pharmaceutical treatments. From a critical analysis - particularly of the clinical studies presented - conclusions are drawn for the therapy of hearing disorders in the future.lld:pubmed
pubmed-article:22073049pubmed:languageenglld:pubmed
pubmed-article:22073049pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:22073049pubmed:statusPubMed-not-MEDLINElld:pubmed
pubmed-article:22073049pubmed:issn1865-1011lld:pubmed
pubmed-article:22073049pubmed:authorpubmed-author:PlontkeStefan...lld:pubmed
pubmed-article:22073049pubmed:issnTypeElectroniclld:pubmed
pubmed-article:22073049pubmed:volume4lld:pubmed
pubmed-article:22073049pubmed:ownerNLMlld:pubmed
pubmed-article:22073049pubmed:authorsCompleteYlld:pubmed
pubmed-article:22073049pubmed:paginationDoc01lld:pubmed
pubmed-article:22073049pubmed:year2005lld:pubmed
pubmed-article:22073049pubmed:articleTitleTherapy of hearing disorders - conservative procedures.lld:pubmed
pubmed-article:22073049pubmed:affiliationDepartment of Otorhinolaryngology - Head and Neck Surgery, Tübingen Hearing Research Center (THRC), University of Tübingen, Germany.lld:pubmed
pubmed-article:22073049pubmed:publicationTypeJournal Articlelld:pubmed