| pubmed-article:220045 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:220045 | lifeskim:mentions | umls-concept:C0007635 | lld:lifeskim |
| pubmed-article:220045 | lifeskim:mentions | umls-concept:C0023823 | lld:lifeskim |
| pubmed-article:220045 | lifeskim:mentions | umls-concept:C1167622 | lld:lifeskim |
| pubmed-article:220045 | lifeskim:mentions | umls-concept:C0243144 | lld:lifeskim |
| pubmed-article:220045 | lifeskim:mentions | umls-concept:C2587213 | lld:lifeskim |
| pubmed-article:220045 | lifeskim:mentions | umls-concept:C1550605 | lld:lifeskim |
| pubmed-article:220045 | lifeskim:mentions | umls-concept:C0456205 | lld:lifeskim |
| pubmed-article:220045 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:220045 | pubmed:dateCreated | 1979-7-25 | lld:pubmed |
| pubmed-article:220045 | pubmed:abstractText | The (high-affinity receptor)-mediated uptake of homologous low-density (low-rho) lipoproteins by cultured human arterial smooth muscle cells or human skin fibroblasts is controlled by the sialic acid content of low-rho lipoprotein particles. This conclusion is derived from the following results. 1. Gangliosides incubated with native low-rho lipoproteins associate with low-rho lipoprotein particles. Low-rho lipoproteins modified by associated GLac1, GGtet1, and GGtet2b + GGtet3 gangliosides are internalized by arterial smooth muscle cells at a rate up to 80% lower than native low-rho lipoproteins or those preincubated with desialized gangliosides. 2. The inhibitory effect of gangliosides is specific for high affinity uptake and not detectable on skin fibroblasts deficient in low-rho-lipoprotein receptor. 3. Desialyzed low-rho lipoproteins are internalized by smooth muscle cells up to 100% faster than native low-rho lipoproteins, the enhancement of uptake corresponding to the degree of desialization. | lld:pubmed |
| pubmed-article:220045 | pubmed:language | eng | lld:pubmed |
| pubmed-article:220045 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:220045 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:220045 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:220045 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:220045 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:220045 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:220045 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:220045 | pubmed:issn | 0014-2956 | lld:pubmed |
| pubmed-article:220045 | pubmed:author | pubmed-author:MrazWW | lld:pubmed |
| pubmed-article:220045 | pubmed:author | pubmed-author:WiegandtHH | lld:pubmed |
| pubmed-article:220045 | pubmed:author | pubmed-author:BuddeckeEE | lld:pubmed |
| pubmed-article:220045 | pubmed:author | pubmed-author:FilipovicII | lld:pubmed |
| pubmed-article:220045 | pubmed:author | pubmed-author:SchwarzmannGG | lld:pubmed |
| pubmed-article:220045 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:220045 | pubmed:day | 2 | lld:pubmed |
| pubmed-article:220045 | pubmed:volume | 93 | lld:pubmed |
| pubmed-article:220045 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:220045 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:220045 | pubmed:pagination | 51-5 | lld:pubmed |
| pubmed-article:220045 | pubmed:dateRevised | 2007-7-23 | lld:pubmed |
| pubmed-article:220045 | pubmed:meshHeading | pubmed-meshheading:220045-H... | lld:pubmed |
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| pubmed-article:220045 | pubmed:meshHeading | pubmed-meshheading:220045-F... | lld:pubmed |
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| pubmed-article:220045 | pubmed:meshHeading | pubmed-meshheading:220045-G... | lld:pubmed |
| pubmed-article:220045 | pubmed:meshHeading | pubmed-meshheading:220045-B... | lld:pubmed |
| pubmed-article:220045 | pubmed:meshHeading | pubmed-meshheading:220045-P... | lld:pubmed |
| pubmed-article:220045 | pubmed:meshHeading | pubmed-meshheading:220045-L... | lld:pubmed |
| pubmed-article:220045 | pubmed:meshHeading | pubmed-meshheading:220045-S... | lld:pubmed |
| pubmed-article:220045 | pubmed:year | 1979 | lld:pubmed |
| pubmed-article:220045 | pubmed:articleTitle | Sialic-acid content of low-density lipoproteins controls their binding and uptake by cultured cells. | lld:pubmed |
| pubmed-article:220045 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:220045 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:220045 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:220045 | lld:pubmed |
