pubmed-article:2194462 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:2194462 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
pubmed-article:2194462 | lifeskim:mentions | umls-concept:C1257890 | lld:lifeskim |
pubmed-article:2194462 | lifeskim:mentions | umls-concept:C0020792 | lld:lifeskim |
pubmed-article:2194462 | lifeskim:mentions | umls-concept:C0009325 | lld:lifeskim |
pubmed-article:2194462 | lifeskim:mentions | umls-concept:C0016030 | lld:lifeskim |
pubmed-article:2194462 | lifeskim:mentions | umls-concept:C0011644 | lld:lifeskim |
pubmed-article:2194462 | lifeskim:mentions | umls-concept:C0441889 | lld:lifeskim |
pubmed-article:2194462 | lifeskim:mentions | umls-concept:C1533691 | lld:lifeskim |
pubmed-article:2194462 | pubmed:issue | 6 | lld:pubmed |
pubmed-article:2194462 | pubmed:dateCreated | 1990-8-6 | lld:pubmed |
pubmed-article:2194462 | pubmed:abstractText | A subpopulation of scleroderma dermal fibroblasts was identified by flow cytometric analysis. Between 15% and 25% of the cells within the scleroderma fibroblast lines had high levels of cytoplasmic granularity, as identified by side light scatter characteristics. Similar fibroblasts composed less than 3% of the cells within the normal fibroblast lines, although greater numbers could be induced through exposure to soluble factors derived from activated mononuclear cells. The granular subpopulation of fibroblasts produced 2-3 times as much procollagen as did the other fibroblasts. These data support the hypothesis that fibrosis in scleroderma may result in part from the activity of an inherently high procollagen-producing subset of normal fibroblasts that is expanded through exposure to immune cytokines. | lld:pubmed |
pubmed-article:2194462 | pubmed:language | eng | lld:pubmed |
pubmed-article:2194462 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2194462 | pubmed:citationSubset | AIM | lld:pubmed |
pubmed-article:2194462 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2194462 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2194462 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2194462 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2194462 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:2194462 | pubmed:month | Jun | lld:pubmed |
pubmed-article:2194462 | pubmed:issn | 0004-3591 | lld:pubmed |
pubmed-article:2194462 | pubmed:author | pubmed-author:OrdonezJ VJV | lld:pubmed |
pubmed-article:2194462 | pubmed:author | pubmed-author:ChoiJJ | lld:pubmed |
pubmed-article:2194462 | pubmed:author | pubmed-author:TaramelliDD | lld:pubmed |
pubmed-article:2194462 | pubmed:author | pubmed-author:NeedlemanB... | lld:pubmed |
pubmed-article:2194462 | pubmed:author | pubmed-author:AlmiAA | lld:pubmed |
pubmed-article:2194462 | pubmed:author | pubmed-author:GayerKK | lld:pubmed |
pubmed-article:2194462 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:2194462 | pubmed:volume | 33 | lld:pubmed |
pubmed-article:2194462 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:2194462 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:2194462 | pubmed:pagination | 842-52 | lld:pubmed |
pubmed-article:2194462 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
pubmed-article:2194462 | pubmed:meshHeading | pubmed-meshheading:2194462-... | lld:pubmed |
pubmed-article:2194462 | pubmed:meshHeading | pubmed-meshheading:2194462-... | lld:pubmed |
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pubmed-article:2194462 | pubmed:meshHeading | pubmed-meshheading:2194462-... | lld:pubmed |
pubmed-article:2194462 | pubmed:meshHeading | pubmed-meshheading:2194462-... | lld:pubmed |
pubmed-article:2194462 | pubmed:year | 1990 | lld:pubmed |
pubmed-article:2194462 | pubmed:articleTitle | In vitro identification of a subpopulation of fibroblasts that produces high levels of collagen in scleroderma patients. | lld:pubmed |
pubmed-article:2194462 | pubmed:affiliation | Department of Medicine, University of Maryland School of Medicine, Baltimore. | lld:pubmed |
pubmed-article:2194462 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:2194462 | pubmed:publicationType | Comparative Study | lld:pubmed |
pubmed-article:2194462 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2194462 | lld:pubmed |