Linked Life Data

21813742

Source:http://linkedlifedata.com/resource/pubmed/id/21813742

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pubmed-article:21813742pubmed:dateCreated2011-9-20lld:pubmed
pubmed-article:21813742pubmed:abstractTextTo assess the prognostic implications of mediastinal positron emission tomographic (PET) findings in patients undergoing curative resection of non-small cell lung cancer (NSCLC) who have histologically negative mediastinal lymph nodes (LNs), with the hypothesis that positive findings at PET are prognostic even in patients with negative histologic findings in the LNs. Materials and Methods: Records of patients with a preoperative PET undergoing curative surgery, without adjuvant radiation, for pathologic T1-3N0-1 NSCLC at the University of North Carolina between 2000 and 2006 were reviewed as an institutional review board-approved HIPAA-compliant retrospective study. Ninety patients were evaluable (all histologically negative in mediastinum; 44 with both mediastinoscopy and surgery); 13 patients had positive mediastinal PET findings, and 77 had negative mediastinal PET findings. Local-regional and distant failure rates in patients with and those without mediastinal abnormalities at preoperative PET were compared by using logistic regression and log-rank tests.lld:pubmed
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pubmed-article:21813742pubmed:authorpubmed-author:MarksLawrence...lld:pubmed
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pubmed-article:21813742pubmed:authorpubmed-author:FriedDavid...lld:pubmed
pubmed-article:21813742pubmed:authorpubmed-author:ChiuWing...lld:pubmed
pubmed-article:21813742pubmed:authorpubmed-author:LawrenceMicha...lld:pubmed
pubmed-article:21813742pubmed:copyrightInfo© RSNA, 2011.lld:pubmed
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pubmed-article:21813742pubmed:volume261lld:pubmed
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pubmed-article:21813742pubmed:year2011lld:pubmed
pubmed-article:21813742pubmed:articleTitleNon-small cell lung cancer: prognostic importance of positive FDG PET findings in the mediastinum for patients with N0-N1 disease at pathologic analysis.lld:pubmed
pubmed-article:21813742pubmed:affiliationDepartment of Radiation Oncology, University of North Carolina School of Medicine, Chapel Hill, NC 27514, USA.lld:pubmed
pubmed-article:21813742pubmed:publicationTypeJournal Articlelld:pubmed