| pubmed-article:21785644 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:21785644 | lifeskim:mentions | umls-concept:C1029824 | lld:lifeskim |
| pubmed-article:21785644 | lifeskim:mentions | umls-concept:C0016767 | lld:lifeskim |
| pubmed-article:21785644 | lifeskim:mentions | umls-concept:C1510451 | lld:lifeskim |
| pubmed-article:21785644 | lifeskim:mentions | umls-concept:C0032594 | lld:lifeskim |
| pubmed-article:21785644 | lifeskim:mentions | umls-concept:C0441655 | lld:lifeskim |
| pubmed-article:21785644 | lifeskim:mentions | umls-concept:C1995017 | lld:lifeskim |
| pubmed-article:21785644 | pubmed:dateCreated | 2011-7-25 | lld:pubmed |
| pubmed-article:21785644 | pubmed:abstractText | A water-soluble polysaccharide (BIWS-4b) was purified from the fruit bodies of Bulgaria inquinans (Fries). It is composed of mannose (27.2%), glucose (15.5%) and galactose (57.3%). Its molecular weight was estimated to be 7.4?kDa (polydispersity index, Mw/Mn: 1.35). Structural analyses indicated that BIWS-4b mainly contains (1 ? 6)-linked, (1 ? 5)-linked and (1 ? 5,6)-linked ?-Galf units; (1 ? 4)-linked and non-reducing terminal ?-Glcp units; and (1 ? 2)-linked, (1 ? 6)-linked, (1 ? 2,6)-linked and non-reducing terminal ?-Manp units. When examined by the 4-day method and in a prophylactic assay in mice, BIWS-4b exhibited markedly suppressive activity against malaria while enhancing the activity of artesunate. Immunological tests indicated that BIWS-4b significantly enhanced macrophage phagocytosis and splenic lymphocyte proliferation in malaria-bearing mice and normal mice. The anti-malarial activity of BIWS-4b might be intermediated by enhancing immune competence and restoring artesunate-suppressed immune function. Thus, BIWS-4b is a potential adjuvant of anti-malaria drugs. | lld:pubmed |
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| pubmed-article:21785644 | pubmed:language | eng | lld:pubmed |
| pubmed-article:21785644 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21785644 | pubmed:status | PubMed-not-MEDLINE | lld:pubmed |
| pubmed-article:21785644 | pubmed:issn | 1741-4288 | lld:pubmed |
| pubmed-article:21785644 | pubmed:author | pubmed-author:MoenL KLK | lld:pubmed |
| pubmed-article:21785644 | pubmed:author | pubmed-author:SunP CPC | lld:pubmed |
| pubmed-article:21785644 | pubmed:author | pubmed-author:DaleT JTJ | lld:pubmed |
| pubmed-article:21785644 | pubmed:author | pubmed-author:XXX | lld:pubmed |
| pubmed-article:21785644 | pubmed:author | pubmed-author:NiWeihuaW | lld:pubmed |
| pubmed-article:21785644 | pubmed:author | pubmed-author:ZhuJingjingJ | lld:pubmed |
| pubmed-article:21785644 | pubmed:author | pubmed-author:BiHongtaoH | lld:pubmed |
| pubmed-article:21785644 | pubmed:author | pubmed-author:GaoTingtingT | lld:pubmed |
| pubmed-article:21785644 | pubmed:author | pubmed-author:LiZonghongZ | lld:pubmed |
| pubmed-article:21785644 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:21785644 | pubmed:volume | 2011 | lld:pubmed |
| pubmed-article:21785644 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:21785644 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:21785644 | pubmed:pagination | 973460 | lld:pubmed |
| pubmed-article:21785644 | pubmed:year | 2011 | lld:pubmed |
| pubmed-article:21785644 | pubmed:articleTitle | A Water-Soluble Polysaccharide from the Fruit Bodies of Bulgaria inquinans (Fries) and Its Anti-Malarial Activity. | lld:pubmed |
| pubmed-article:21785644 | pubmed:affiliation | School of Life Sciences, Northeast Normal University, Changchun 130024, China. | lld:pubmed |
| pubmed-article:21785644 | pubmed:publicationType | Journal Article | lld:pubmed |
