Linked Life Data

21776267

Source:http://linkedlifedata.com/resource/pubmed/id/21776267

Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:21776267rdf:typepubmed:Citationlld:pubmed
pubmed-article:21776267lifeskim:mentionsumls-concept:C0030705lld:lifeskim
pubmed-article:21776267lifeskim:mentionsumls-concept:C0003864lld:lifeskim
pubmed-article:21776267lifeskim:mentionsumls-concept:C0003211lld:lifeskim
pubmed-article:21776267lifeskim:mentionsumls-concept:C0020740lld:lifeskim
pubmed-article:21776267lifeskim:mentionsumls-concept:C1280500lld:lifeskim
pubmed-article:21776267lifeskim:mentionsumls-concept:C0538927lld:lifeskim
pubmed-article:21776267lifeskim:mentionsumls-concept:C0439658lld:lifeskim
pubmed-article:21776267lifeskim:mentionsumls-concept:C0439858lld:lifeskim
pubmed-article:21776267pubmed:dateCreated2011-7-21lld:pubmed
pubmed-article:21776267pubmed:abstractTextBackground. Arthritis is a common condition that co-exists in the elderly population. This condition leads to frequent administration of comorbid analgesics especially non steroidal anti-inflammatory drugs (NSAIDs). Aim. To study cardiorenal toxicity of celecoxib versus ibuprofen in arthritic patients. Subjects and Methods. Seven hundred ninety-wo arthritic patients were enrolled in the study for 6 months. Three hundred ninety-six patients administered celecoxib 400?mg twice a day; 396 patients administered ibuprofen 300?mg three times a day. Effects measured included investigator-reported hypertension, edema, or congestive heart failure, increases in serum creatinine or reduction in serum creatinine clearance, and changes in serum electrolytes. Results. Celecoxib was associated with significant (P < .05) lower incidence of hypertension and edema in comparison with ibuprofen. Systolic hypertension occurred significantly less (P < .05) with celecoxib compared with ibuprofen. Serum creatinine was significantly increased (P < .05) in patients treated with ibuprofen in comparison with celecoxib. Creatinine clearance was significantly lower (P < .05) in cases treated with ibuprofen in comparison to celecoxib. Nonsignificant changes in serum body electrolytes occurred. Conclusion. The most important finding of this study was the lowering incidence of cardiorenal toxicity of celecoxib in comparison with ibuprofen.lld:pubmed
pubmed-article:21776267pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:21776267pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:21776267pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:21776267pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:21776267pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:21776267pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:21776267pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:21776267pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:21776267pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:21776267pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:21776267pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:21776267pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:21776267pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:21776267pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:21776267pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:21776267pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:21776267pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:21776267pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:21776267pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:21776267pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:21776267pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:21776267pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:21776267pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:21776267pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:21776267pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:21776267pubmed:languageenglld:pubmed
pubmed-article:21776267pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:21776267pubmed:statusPubMed-not-MEDLINElld:pubmed
pubmed-article:21776267pubmed:issn1687-8205lld:pubmed
pubmed-article:21776267pubmed:authorpubmed-author:HegazyRagiaRlld:pubmed
pubmed-article:21776267pubmed:authorpubmed-author:AlashhabMoham...lld:pubmed
pubmed-article:21776267pubmed:authorpubmed-author:AminMadihaMlld:pubmed
pubmed-article:21776267pubmed:issnTypeElectroniclld:pubmed
pubmed-article:21776267pubmed:volume2011lld:pubmed
pubmed-article:21776267pubmed:ownerNLMlld:pubmed
pubmed-article:21776267pubmed:authorsCompleteYlld:pubmed
pubmed-article:21776267pubmed:pagination862153lld:pubmed
pubmed-article:21776267pubmed:year2011lld:pubmed
pubmed-article:21776267pubmed:articleTitleCardiorenal Effects of Newer NSAIDs (Celecoxib) versus Classic NSAIDs (Ibuprofen) in Patients with Arthritis.lld:pubmed
pubmed-article:21776267pubmed:affiliationDepartment of Forensic Medicine and Clinical Toxicology, Benha Faculty of Medicine, Benha University, Benha, Egypt.lld:pubmed
pubmed-article:21776267pubmed:publicationTypeJournal Articlelld:pubmed