| pubmed-article:2177015 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2177015 | lifeskim:mentions | umls-concept:C0006675 | lld:lifeskim |
| pubmed-article:2177015 | lifeskim:mentions | umls-concept:C0012155 | lld:lifeskim |
| pubmed-article:2177015 | lifeskim:mentions | umls-concept:C0021853 | lld:lifeskim |
| pubmed-article:2177015 | lifeskim:mentions | umls-concept:C0022646 | lld:lifeskim |
| pubmed-article:2177015 | lifeskim:mentions | umls-concept:C0006674 | lld:lifeskim |
| pubmed-article:2177015 | lifeskim:mentions | umls-concept:C0008318 | lld:lifeskim |
| pubmed-article:2177015 | lifeskim:mentions | umls-concept:C0031705 | lld:lifeskim |
| pubmed-article:2177015 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:2177015 | lifeskim:mentions | umls-concept:C1709059 | lld:lifeskim |
| pubmed-article:2177015 | lifeskim:mentions | umls-concept:C0054444 | lld:lifeskim |
| pubmed-article:2177015 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:2177015 | pubmed:dateCreated | 1991-2-25 | lld:pubmed |
| pubmed-article:2177015 | pubmed:abstractText | Synthetic oligonucleotide probes complementary to chick calbindin-28 kDa-mRNA were used to study the latter's regulation and relationship to calbindin in the chick. The effects of vitamin D3 sources and dietary alteration on the genomic expression were characterized by Northern blot and solution hybridization. Intestinal calbindin and its mRNA were almost absent in vitamin D-deficient chicks and were not affected by dietary alteration. Renal calbindin and its mRNA were lower in the vitamin D-deficient than in vitamin D3- or 1,25-dihydroxyvitamin D3 (1,25(OH)2D3)-fed chicks. In the same animal, renal calbindin mRNA and calbindin were higher than intestinal. In vitamin D3-fed chicks, dietary calcium (Ca) or phosphorus (P) restriction induced, and high dietary Ca inhibited, intestinal calbindin and its mRNA synthesis. In the same chicks, dietary P restriction induced renal calbindin mRNA and calbindin synthesis. In 1,25-(OH)2D3-fed chicks, dietary P restriction induced and high dietary Ca inhibited the synthesis of intestinal and renal calbindin. The results suggest that: (a) most of the changes in renal and intestinal calbindin could be attributed to the changes in the mRNA; (b) the adaptation to dietary Ca and P alterations requires vitamin D metabolites; (c) high dietary Ca affects intestinal and renal calbindin-mRNA and calbindin via mechanisms independent of kidney 1-hydroxylase; and (d) plasma Ca and renal calbindin or its mRNA tend to change together in vitamin D-deficient or vitamin D3-fed, but not in 1,25(OH)2D3-fed chicks. | lld:pubmed |
| pubmed-article:2177015 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2177015 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2177015 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2177015 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2177015 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2177015 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2177015 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2177015 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2177015 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2177015 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2177015 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2177015 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2177015 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:2177015 | pubmed:issn | 0303-7207 | lld:pubmed |
| pubmed-article:2177015 | pubmed:author | pubmed-author:BarAA | lld:pubmed |
| pubmed-article:2177015 | pubmed:author | pubmed-author:FullmerC SCS | lld:pubmed |
| pubmed-article:2177015 | pubmed:author | pubmed-author:BrindakM EME | lld:pubmed |
| pubmed-article:2177015 | pubmed:author | pubmed-author:ShaniMM | lld:pubmed |
| pubmed-article:2177015 | pubmed:author | pubmed-author:StriemSS | lld:pubmed |
| pubmed-article:2177015 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2177015 | pubmed:day | 30 | lld:pubmed |
| pubmed-article:2177015 | pubmed:volume | 72 | lld:pubmed |
| pubmed-article:2177015 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2177015 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2177015 | pubmed:pagination | 23-31 | lld:pubmed |
| pubmed-article:2177015 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:2177015 | pubmed:meshHeading | pubmed-meshheading:2177015-... | lld:pubmed |
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| pubmed-article:2177015 | pubmed:meshHeading | pubmed-meshheading:2177015-... | lld:pubmed |
| pubmed-article:2177015 | pubmed:meshHeading | pubmed-meshheading:2177015-... | lld:pubmed |
| pubmed-article:2177015 | pubmed:meshHeading | pubmed-meshheading:2177015-... | lld:pubmed |
| pubmed-article:2177015 | pubmed:meshHeading | pubmed-meshheading:2177015-... | lld:pubmed |
| pubmed-article:2177015 | pubmed:meshHeading | pubmed-meshheading:2177015-... | lld:pubmed |
| pubmed-article:2177015 | pubmed:year | 1990 | lld:pubmed |
| pubmed-article:2177015 | pubmed:articleTitle | Modulation of chick intestinal and renal calbindin gene expression by dietary vitamin D3, 1,25-dihydroxyvitamin D3, calcium and phosphorus. | lld:pubmed |
| pubmed-article:2177015 | pubmed:affiliation | Institute of Animal Science, ARO, Volcani Center, Bet Dagan, Israel. | lld:pubmed |
| pubmed-article:2177015 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2177015 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| pubmed-article:2177015 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2177015 | lld:pubmed |
