| pubmed-article:21762439 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:21762439 | lifeskim:mentions | umls-concept:C0003286 | lld:lifeskim |
| pubmed-article:21762439 | lifeskim:mentions | umls-concept:C0259972 | lld:lifeskim |
| pubmed-article:21762439 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:21762439 | lifeskim:mentions | umls-concept:C0295893 | lld:lifeskim |
| pubmed-article:21762439 | lifeskim:mentions | umls-concept:C1419346 | lld:lifeskim |
| pubmed-article:21762439 | lifeskim:mentions | umls-concept:C1611645 | lld:lifeskim |
| pubmed-article:21762439 | lifeskim:mentions | umls-concept:C0003299 | lld:lifeskim |
| pubmed-article:21762439 | pubmed:issue | 9 | lld:pubmed |
| pubmed-article:21762439 | pubmed:dateCreated | 2011-9-8 | lld:pubmed |
| pubmed-article:21762439 | pubmed:abstractText | The ketogenic diet (KD) has been used as an effective antiepileptic treatment for nearly a century. Inhibition of glycolysis and increased levels of ketone bodies are both known to contribute to the antiepileptic effects of the KD. Neuron-restrictive silencer factor (NRSF), also known as RE-1 silencing transcription factor (REST), is implicated in the antiepileptic effects of the glycolytic inhibitor 2-deoxy-d-glucose (2DG). Glycolytic inhibition is a common feature of the KD and 2DG treatment, leading to the hypothesis that NRSF might also be involved in the antiepileptic effect of the KD. To test this hypothesis, the present study was designed to investigate the role of NRSF in the antiepileptic effect of 2DG, the KD, and acetone in vivo. | lld:pubmed |
| pubmed-article:21762439 | pubmed:language | eng | lld:pubmed |
| pubmed-article:21762439 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21762439 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:21762439 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21762439 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21762439 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21762439 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21762439 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21762439 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21762439 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21762439 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:21762439 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:21762439 | pubmed:issn | 1528-1167 | lld:pubmed |
| pubmed-article:21762439 | pubmed:author | pubmed-author:FeiJianJ | lld:pubmed |
| pubmed-article:21762439 | pubmed:author | pubmed-author:XiongZhi-QiZQ | lld:pubmed |
| pubmed-article:21762439 | pubmed:author | pubmed-author:HuXiao-LingXL | lld:pubmed |
| pubmed-article:21762439 | pubmed:author | pubmed-author:ChengXuewenX | lld:pubmed |
| pubmed-article:21762439 | pubmed:copyrightInfo | Wiley Periodicals, Inc. © 2011 International League Against Epilepsy. | lld:pubmed |
| pubmed-article:21762439 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:21762439 | pubmed:volume | 52 | lld:pubmed |
| pubmed-article:21762439 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:21762439 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:21762439 | pubmed:pagination | 1609-16 | lld:pubmed |
| pubmed-article:21762439 | pubmed:meshHeading | pubmed-meshheading:21762439... | lld:pubmed |
| pubmed-article:21762439 | pubmed:meshHeading | pubmed-meshheading:21762439... | lld:pubmed |
| pubmed-article:21762439 | pubmed:meshHeading | pubmed-meshheading:21762439... | lld:pubmed |
| pubmed-article:21762439 | pubmed:meshHeading | pubmed-meshheading:21762439... | lld:pubmed |
| pubmed-article:21762439 | pubmed:meshHeading | pubmed-meshheading:21762439... | lld:pubmed |
| pubmed-article:21762439 | pubmed:meshHeading | pubmed-meshheading:21762439... | lld:pubmed |
| pubmed-article:21762439 | pubmed:meshHeading | pubmed-meshheading:21762439... | lld:pubmed |
| pubmed-article:21762439 | pubmed:meshHeading | pubmed-meshheading:21762439... | lld:pubmed |
| pubmed-article:21762439 | pubmed:meshHeading | pubmed-meshheading:21762439... | lld:pubmed |
| pubmed-article:21762439 | pubmed:meshHeading | pubmed-meshheading:21762439... | lld:pubmed |
| pubmed-article:21762439 | pubmed:meshHeading | pubmed-meshheading:21762439... | lld:pubmed |
| pubmed-article:21762439 | pubmed:meshHeading | pubmed-meshheading:21762439... | lld:pubmed |
| pubmed-article:21762439 | pubmed:meshHeading | pubmed-meshheading:21762439... | lld:pubmed |
| pubmed-article:21762439 | pubmed:meshHeading | pubmed-meshheading:21762439... | lld:pubmed |
| pubmed-article:21762439 | pubmed:year | 2011 | lld:pubmed |
| pubmed-article:21762439 | pubmed:articleTitle | Neuron-restrictive silencer factor is not required for the antiepileptic effect of the ketogenic diet. | lld:pubmed |
| pubmed-article:21762439 | pubmed:affiliation | Institute of Neuroscience and State Key Laboratory of Neuroscience, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China. | lld:pubmed |
| pubmed-article:21762439 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:21762439 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:19712 | entrezgene:pubmed | pubmed-article:21762439 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:21762439 | lld:entrezgene |
