| pubmed-article:2167232 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2167232 | lifeskim:mentions | umls-concept:C0205145 | lld:lifeskim |
| pubmed-article:2167232 | lifeskim:mentions | umls-concept:C0026882 | lld:lifeskim |
| pubmed-article:2167232 | lifeskim:mentions | umls-concept:C0035331 | lld:lifeskim |
| pubmed-article:2167232 | lifeskim:mentions | umls-concept:C0008630 | lld:lifeskim |
| pubmed-article:2167232 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:2167232 | pubmed:dateCreated | 1990-9-27 | lld:pubmed |
| pubmed-article:2167232 | pubmed:abstractText | In the inherited degenerative retinal disease of the rd mouse, rod cGMP levels rise above normal due to depressed cGMP-phosphodiesterase (cGMP-PDE) function a few days before degeneration begins. The subnormal activity of the cGMP-PDE may be due to a lesion in the enzyme itself, or in any of several proteins that regulate it. We have used a bovine cDNA for the alpha-subunit of cGMP-PDE to map its gene Pdea to mouse chromosome 18 at a distance of 21 centimorgans (cM) from the Mbp locus. Since the locus of the rd mutation is on mouse chromosome 5, a defect in the Pdea gene is ruled out as the cause of this inherited retinal degeneration. | lld:pubmed |
| pubmed-article:2167232 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2167232 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2167232 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2167232 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2167232 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2167232 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2167232 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2167232 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2167232 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:2167232 | pubmed:issn | 0014-4835 | lld:pubmed |
| pubmed-article:2167232 | pubmed:author | pubmed-author:LOJJ | lld:pubmed |
| pubmed-article:2167232 | pubmed:author | pubmed-author:FarberD BDB | lld:pubmed |
| pubmed-article:2167232 | pubmed:author | pubmed-author:AppleburyM... | lld:pubmed |
| pubmed-article:2167232 | pubmed:author | pubmed-author:KozakC ACA | lld:pubmed |
| pubmed-article:2167232 | pubmed:author | pubmed-author:DancigerMM | lld:pubmed |
| pubmed-article:2167232 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2167232 | pubmed:volume | 51 | lld:pubmed |
| pubmed-article:2167232 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2167232 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2167232 | pubmed:pagination | 185-9 | lld:pubmed |
| pubmed-article:2167232 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
| pubmed-article:2167232 | pubmed:meshHeading | pubmed-meshheading:2167232-... | lld:pubmed |
| pubmed-article:2167232 | pubmed:meshHeading | pubmed-meshheading:2167232-... | lld:pubmed |
| pubmed-article:2167232 | pubmed:meshHeading | pubmed-meshheading:2167232-... | lld:pubmed |
| pubmed-article:2167232 | pubmed:meshHeading | pubmed-meshheading:2167232-... | lld:pubmed |
| pubmed-article:2167232 | pubmed:meshHeading | pubmed-meshheading:2167232-... | lld:pubmed |
| pubmed-article:2167232 | pubmed:meshHeading | pubmed-meshheading:2167232-... | lld:pubmed |
| pubmed-article:2167232 | pubmed:meshHeading | pubmed-meshheading:2167232-... | lld:pubmed |
| pubmed-article:2167232 | pubmed:meshHeading | pubmed-meshheading:2167232-... | lld:pubmed |
| pubmed-article:2167232 | pubmed:year | 1990 | lld:pubmed |
| pubmed-article:2167232 | pubmed:articleTitle | Genetic mapping demonstrates that the alpha-subunit of retinal cGMP-phosphodiesterase is not the site of the rd mutation. | lld:pubmed |
| pubmed-article:2167232 | pubmed:affiliation | Jules Stein Eye Institute, UCLA School of Medicine 90024-1771. | lld:pubmed |
| pubmed-article:2167232 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2167232 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:2167232 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:17196 | entrezgene:pubmed | pubmed-article:2167232 | lld:entrezgene |
| entrez-gene:18587 | entrezgene:pubmed | pubmed-article:2167232 | lld:entrezgene |
| entrez-gene:225600 | entrezgene:pubmed | pubmed-article:2167232 | lld:entrezgene |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2167232 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2167232 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2167232 | lld:pubmed |
