| pubmed-article:2166783 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2166783 | lifeskim:mentions | umls-concept:C0019704 | lld:lifeskim |
| pubmed-article:2166783 | lifeskim:mentions | umls-concept:C0021311 | lld:lifeskim |
| pubmed-article:2166783 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:2166783 | lifeskim:mentions | umls-concept:C0229671 | lld:lifeskim |
| pubmed-article:2166783 | lifeskim:mentions | umls-concept:C0205494 | lld:lifeskim |
| pubmed-article:2166783 | lifeskim:mentions | umls-concept:C0041249 | lld:lifeskim |
| pubmed-article:2166783 | lifeskim:mentions | umls-concept:C0068527 | lld:lifeskim |
| pubmed-article:2166783 | lifeskim:mentions | umls-concept:C0233401 | lld:lifeskim |
| pubmed-article:2166783 | lifeskim:mentions | umls-concept:C0205216 | lld:lifeskim |
| pubmed-article:2166783 | lifeskim:mentions | umls-concept:C0205217 | lld:lifeskim |
| pubmed-article:2166783 | pubmed:issue | 9 | lld:pubmed |
| pubmed-article:2166783 | pubmed:dateCreated | 1990-9-14 | lld:pubmed |
| pubmed-article:2166783 | pubmed:abstractText | We investigated serum neopterin, tryptophan, and kynurenine concentrations in 23 HIV-1 seropositive patients (Walter Reed Stage 4-6). Ten patients presented with polyneuropathy and three with dementia, one of the patients with dementia also had polyneuropathy and dementia. We found significant associations between lower trytophan concentrations and neurologic/psychiatric symptoms. The negative correlation of tryptophan with kynurenine and neopterin concentrations indicates activity of indoleamine 2,3-dioxygenase (IDO) in patients. IDO can be induced by cytokines such as interferon-gamma and therefore low tryptophan levels may result from chronic immune stimulation in HIV-1 seropositives. | lld:pubmed |
| pubmed-article:2166783 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2166783 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2166783 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2166783 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:2166783 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2166783 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2166783 | pubmed:issn | 0894-9255 | lld:pubmed |
| pubmed-article:2166783 | pubmed:author | pubmed-author:FuchsDD | lld:pubmed |
| pubmed-article:2166783 | pubmed:author | pubmed-author:WernerE RER | lld:pubmed |
| pubmed-article:2166783 | pubmed:author | pubmed-author:WachterHH | lld:pubmed |
| pubmed-article:2166783 | pubmed:author | pubmed-author:StöckleEE | lld:pubmed |
| pubmed-article:2166783 | pubmed:author | pubmed-author:ReibneggerGG | lld:pubmed |
| pubmed-article:2166783 | pubmed:author | pubmed-author:MöllerA AAA | lld:pubmed |
| pubmed-article:2166783 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2166783 | pubmed:volume | 3 | lld:pubmed |
| pubmed-article:2166783 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2166783 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2166783 | pubmed:pagination | 873-6 | lld:pubmed |
| pubmed-article:2166783 | pubmed:dateRevised | 2004-11-17 | lld:pubmed |
| pubmed-article:2166783 | pubmed:meshHeading | pubmed-meshheading:2166783-... | lld:pubmed |
| pubmed-article:2166783 | pubmed:meshHeading | pubmed-meshheading:2166783-... | lld:pubmed |
| pubmed-article:2166783 | pubmed:meshHeading | pubmed-meshheading:2166783-... | lld:pubmed |
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| pubmed-article:2166783 | pubmed:meshHeading | pubmed-meshheading:2166783-... | lld:pubmed |
| pubmed-article:2166783 | pubmed:meshHeading | pubmed-meshheading:2166783-... | lld:pubmed |
| pubmed-article:2166783 | pubmed:meshHeading | pubmed-meshheading:2166783-... | lld:pubmed |
| pubmed-article:2166783 | pubmed:meshHeading | pubmed-meshheading:2166783-... | lld:pubmed |
| pubmed-article:2166783 | pubmed:meshHeading | pubmed-meshheading:2166783-... | lld:pubmed |
| pubmed-article:2166783 | pubmed:meshHeading | pubmed-meshheading:2166783-... | lld:pubmed |
| pubmed-article:2166783 | pubmed:meshHeading | pubmed-meshheading:2166783-... | lld:pubmed |
| pubmed-article:2166783 | pubmed:year | 1990 | lld:pubmed |
| pubmed-article:2166783 | pubmed:articleTitle | Decreased serum tryptophan in patients with HIV-1 infection correlates with increased serum neopterin and with neurologic/psychiatric symptoms. | lld:pubmed |
| pubmed-article:2166783 | pubmed:affiliation | Institute of Medical Chemistry and Biochemistry, University of Innsbruck, Austria. | lld:pubmed |
| pubmed-article:2166783 | pubmed:publicationType | Journal Article | lld:pubmed |
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